Rabbit anti-Human LRRC6 Polyclonal Antibody | anti-LRRC6 antibody

LRRC6, ID (LRRC6, LRTP, TSLRP, Protein TILB homolog, Leucine-rich repeat-containing protein 6, Leucine-rich testis-specific protein, Testis-specific leucine-rich repeat protein) (Azide free) (HRP)

Cat. Num. AAA6317223

• Gene Names: LRRC6; LRTP; TSLRP; CILD19
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: LRRC6; Polyclonal Antibody; ID (LRRC6; LRTP; TSLRP; Protein TILB homolog; Leucine-rich repeat-containing protein 6; Leucine-rich testis-specific protein; Testis-specific leucine-rich repeat protein) (Azide free) (HRP); Testis-specific leucine-rich repeat protein; anti-LRRC6 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).

• Applicable Applications for anti-LRRC6 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: LRRC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from the Central region of human LRRC6.
• Conjugate: HRP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(LRRC6 Antibody (Center) western blot analysis in NCI-H460,A549 cell line lysates (35ug/lane).This demonstrates the LRRC6 antibody detected the LRRC6 protein (arrow).)

Flow Cytometry (FC/FACS)

(LRRC6 Antibody (Center) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Related Product Information for anti-LRRC6 antibody

LRRC6 may be involved in spermatocytogenesis or prophase of meiosis (By similarity).

Product Categories/Family for anti-LRRC6 antibody

Antibodies; Leucine-rich Proteins

References

Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004).

NCBI and Uniprot Product Information

• NCBI GI #: 31621309
• NCBI GeneID: 23639
• NCBI Accession #: NP_036604.2
• NCBI GenBank Nucleotide #: NM_012472.4
• UniProt Accession #: Q86X45; Q13648; Q4G183
• Molecular Weight: 54,255 Da
• NCBI Official Full Name: protein tilB homolog
• NCBI Official Synonym Full Names: leucine rich repeat containing 6
• NCBI Official Symbol: LRRC6
• NCBI Official Synonym Symbols: LRTP; TSLRP; CILD19
• NCBI Protein Information: protein tilB homolog; protein TILB homolog; testis-specific leucine-rich repeat protein
• UniProt Protein Name: Protein tilB homolog
• Protein Family: Protein
• UniProt Gene Name: LRRC6
• UniProt Synonym Gene Names: LRTP; TSLRP
• UniProt Entry Name: TILB_HUMAN

Uniprot Description

LRRC6: Plays a role in motility of cilia. Belongs to the tilb protein family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 8q24.22

Cellular Component: cytoplasm; cilium

Molecular Function: protein binding

Biological Process: sperm motility; male gonad development

Disease: Ciliary Dyskinesia, Primary, 19