Western Blot (WB)
(WB Suggested Anti-FUZ AntibodyTitration: 1.0 ug/mlPositive Control: HepG2 Whole Cell)
Rabbit FUZ Polyclonal Antibody | anti-FUZ antibody
FUZ antibody - C-terminal region
Western Blot (WB)
(WB Suggested Anti-FUZ AntibodyTitration: 1.0 ug/mlPositive Control: HepG2 Whole Cell)
Western Blot (WB)
(WB Suggested Anti-FUZ AntibodyTitration: 1.0 ug/mlPositive Control: HepG2 Whole Cell)
Target Description: FUZ is a probable planar cell polarity effector involved in cilium biogenesis. FUZ may regulate protein and membrane transport to the cilium and may regulate the morphogenesis of hair follicles which depends on functional primary cilia.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a planar cell polarity protein that is involved in ciliogenesis and directional cell movement. Knockout studies in mice exhibit neural tube defects and defective cilia, and mutations in this gene are associated with neural tube defects in humans. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012]
Uniprot Description
FUZ: Probable planar cell polarity effector involved in cilium biogenesis. May regulate protein and membrane transport to the cilium. May regulate the morphogenesis of hair follicles which depends on functional primary cilia. Belongs to the fuzzy family. 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 19q13.33
Cellular Component: cytoskeleton; cytoplasm
Biological Process: spinal cord dorsal/ventral patterning; embryonic skeletal morphogenesis; negative regulation of cell proliferation; embryonic body morphogenesis; protein transport; hair follicle development; sensory cilium biogenesis; neural tube closure; cilium biogenesis; establishment of planar polarity; negative regulation of cell migration; positive regulation of flagellum biogenesis; regulation of smoothened signaling pathway
Disease: Neural Tube Defects
Research Articles on FUZ
Similar Products
Product Notes
The FUZ fuz (Catalog #AAA3216644) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FUZ antibody - C-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FUZ can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the FUZ fuz for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: TVEPLGDKEP SPEQRRRLLR NFYTLVTSTH FPPEPGPPEK TEDEVYQAQL. It is sometimes possible for the material contained within the vial of "FUZ, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
