Rabbit anti-Human LRFN2 Polyclonal Antibody | anti-LRFN2 antibody

LRFN2, CT (LRFN2, KIAA1246, SALM1, Leucine-rich repeat and fibronectin type-III domain-containing protein 2, Synaptic adhesion-like molecule 1) (PE)

Cat. Num. AAA6316888

• Gene Names: LRFN2; SALM1; FIGLER2; KIAA1246
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: LRFN2; Polyclonal Antibody; CT (LRFN2; KIAA1246; SALM1; Leucine-rich repeat and fibronectin type-III domain-containing protein 2; Synaptic adhesion-like molecule 1) (PE); Synaptic adhesion-like molecule 1; anti-LRFN2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-LRFN2 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: LRFN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 629-659 amino acids from the C-terminal region of human LRFN2.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(LRFN2 Antibody (C-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the LRFN2 antibody detected the LRFN2 protein (arrow).)

Related Product Information for anti-LRFN2 antibody

LRFN2 promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity).

Product Categories/Family for anti-LRFN2 antibody

Antibodies; Fibronectin

References

Rose, J. Phd, et al. Mol. Med. (2010). In press: Morimura, N., et al. Gene 380(2):72-83(2006). Wang, C.Y., et al. J. Neurosci. 26(8):2174-2183(2006). Mungall, A.J., et al. Nature 425(6960):805-811(2003).

NCBI and Uniprot Product Information

• NCBI GI #: 55741571
• NCBI GeneID: 57497
• NCBI Accession #: NP_065788.1
• NCBI GenBank Nucleotide #: NM_020737.1
• UniProt Accession #: Q9ULH4; Q5SYP9; A5PKU3
• Molecular Weight: 84,731 Da
• NCBI Official Full Name: leucine-rich repeat and fibronectin type-III domain-containing protein 2
• NCBI Official Synonym Full Names: leucine rich repeat and fibronectin type III domain containing 2
• NCBI Official Symbol: LRFN2
• NCBI Official Synonym Symbols: SALM1; FIGLER2; KIAA1246
• NCBI Protein Information: leucine-rich repeat and fibronectin type-III domain-containing protein 2; synaptic adhesion-like molecule 1; fibronectin type III, immunoglobulin and leucine rich repeat domains 2
• UniProt Protein Name: Leucine-rich repeat and fibronectin type-III domain-containing protein 2
• Protein Family: Leucine-rich repeat and fibronectin type-III domain-containing protein
• UniProt Gene Name: LRFN2
• UniProt Synonym Gene Names: KIAA1246; SALM1
• UniProt Entry Name: LRFN2_HUMAN

Uniprot Description

LRFN2: Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery. Belongs to the LRFN family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 6p21.2-p21.1

Cellular Component: postsynaptic membrane; integral to membrane; cell junction