Rabbit anti-Human LRCH4 Polyclonal Antibody | anti-LRCH4 antibody

LRCH4 Antibody (Center)

Cat. Num. AAA9217342

• Gene Names: LRCH4; LRN; LRRN1; LRRN4; PP14183
• Reactivity: Human
• Applications: Western Blot, ELISA
• Synonyms: LRCH4; Polyclonal Antibody; LRCH4 Antibody (Center); Leucine-rich repeat and calponin homology domain-containing protein 4; Leucine-rich repeat neuronal protein 4; Leucine-rich neuronal protein; LRN; LRRN1; LRRN4; Purified Rabbit Polyclonal Antibody (Pab); anti-LRCH4 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: Ig
• Specificity: This LRCH4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 305-348 amino acids from the Central region of human LRCH4.
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: 0.97 (varies by lot)
• Sequence Length: 683

• Applicable Applications for anti-LRCH4 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB~~1:2000
• Antigen Type: Synthesized Peptide
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(All lanes : Anti-LRCH4 Antibody (Center) at 1:2000 dilutionLane 1: Hela whole cell lysateLane 2: HL-60 whole cell lysateLane 3: THP-1 whole cell lysateLane 4: CCRF-CEM whole cell lysateLane 5: SH-SY5Y whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 74 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Product Categories/Family for anti-LRCH4 antibody

Cell Biology

References

Gloeckner G.,et al.Genome Res. 8:1060-1073(1998). Scherer S.W.,et al.Science 300:767-772(2003). Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).

NCBI and Uniprot Product Information

• NCBI GI #: 49035987
• NCBI GeneID: 4034
• UniProt Accession #: O75427; Q8WV85; Q96ID0; A4D2D5
• Molecular Weight: 73450 Da
• NCBI Official Full Name: Leucine-rich repeat and calponin homology domain-containing protein 4
• NCBI Official Synonym Full Names: leucine rich repeats and calponin homology domain containing 4
• NCBI Official Symbol: LRCH4
• NCBI Official Synonym Symbols: LRN; LRRN1; LRRN4; PP14183
• NCBI Protein Information: leucine-rich repeat and calponin homology domain-containing protein 4
• UniProt Protein Name: Leucine-rich repeat and calponin homology domain-containing protein 4
• Protein Family: Leucine-rich repeat and calponin homology domain-containing protein
• UniProt Gene Name: LRCH4
• UniProt Synonym Gene Names: LRN; LRRN1; LRRN4; Leucine-rich neuronal protein
• UniProt Entry Name: LRCH4_HUMAN

NCBI Description

This gene encodes a protein that contains leucine-rich repeats (LRR) at its amino terminus and that is known to be involved in ligand binding. The carboxyl terminus may act as a membrane anchor. Identified structural elements suggest that the encoded protein resembles a receptor. [provided by RefSeq, Jul 2008]

Uniprot Description

LRCH4:

Protein type: Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 7q22

Cellular Component: PML body

Molecular Function: protein binding

Biological Process: nervous system development