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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human placenta using at dilution of 1:20.)

Rabbit anti-Human Lipopolysaccharide-responsive and beige-like anchor protein Polyclonal Antibody | anti-LRBA antibody

Lipopolysaccharide-responsive and beige-like anchor protein Polyclonal Antibody

Gene Names
LRBA; BGL; LBA; CDC4L; CVID8; LAB300
Reactivity
Human
Applications
Immunohistochemistry
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Synonyms
Lipopolysaccharide-responsive and beige-like anchor protein; Polyclonal Antibody; Lipopolysaccharide-responsive and beige-like anchor protein Polyclonal Antibody; Beige-like protein; CDC4-like protein; LRBA; BGL; CDC4L; LBA; anti-LRBA antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total Lipopolysaccharide-responsive and beige-like anchor protein polyclonal antibody.
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
2851
Applicable Applications for anti-LRBA antibody
Immunohistochemistry (IHC)
Application Notes
Immunohistochemistry: 1:20 - 1:200
Immunogen
Recombinant Human Lipopolysaccharide-responsive and beige-like anchor protein
Immunogen Type
Protein
Preparation and Storage
Store at -20 degree C

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human placenta using at dilution of 1:20.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human placenta using at dilution of 1:20.)
Related Product Information for anti-LRBA antibody
May be involved in coupling signal transduction and vesicle trafficking to enable polarized secretion and/or membrane deposition of immune effector molecules
Product Categories/Family for anti-LRBA antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
987
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
317,702 Da
NCBI Official Full Name
lipopolysaccharide-responsive and beige-like anchor protein isoform 1
NCBI Official Synonym Full Names
LPS responsive beige-like anchor protein
NCBI Official Symbol
LRBA
NCBI Official Synonym Symbols
BGL; LBA; CDC4L; CVID8; LAB300
NCBI Protein Information
lipopolysaccharide-responsive and beige-like anchor protein
UniProt Protein Name
Lipopolysaccharide-responsive and beige-like anchor protein
UniProt Gene Name
LRBA
UniProt Synonym Gene Names
BGL; CDC4L; LBA
UniProt Entry Name
LRBA_HUMAN

Uniprot Description

LRBA: May be involved in coupling signal transduction and vesicle trafficking to enable polarized secretion and/or membrane deposition of immune effector molecules. Defects in LRBA are the cause of immunodeficiency, common variable, type 8, with autoimmunity (CVID8). An autosomal recessive immunologic disorder associated with defective B-cell differentiation and decreased or absent antibody production. Affected individuals have early-childhood onset of recurrent infections, particularly respiratory infections, and also develop variable autoimmune disorders, including idiopathic thrombocytopenic purpura, autoimmune hemolytic anemia, and inflammatory bowel disease. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q31.3

Cellular Component: membrane

Disease: Immunodeficiency, Common Variable, 8, With Autoimmunity

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Product Notes

The LRBA lrba (Catalog #AAA9416370) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Lipopolysaccharide-responsive and beige-like anchor protein Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Lipopolysaccharide-responsive and beige-like anchor protein can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). Immunohistochemistry: 1:20 - 1:200. Researchers should empirically determine the suitability of the LRBA lrba for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Lipopolysaccharide-responsive and beige-like anchor protein, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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