Immunohistochemistry (IHC)
(Immunochemical staining of mouse LIPA in mouse liver with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Mouse LIPA Polyclonal Antibody | anti-LIPA antibody
Anti-LIPA Antibody, Rabbit Polyclonal
Gene Names
Lipa; Lal; Lip1; Lip-1; AA960673
Reactivity
Mouse
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
LIPA; Polyclonal Antibody; Anti-LIPA Antibody; Rabbit Polyclonal; LIPA Antibody; Rabbit PAb; Antigen Affinity Purified; lipase A; lysosomal acid; cholesterol esterase; Anti-AA960673 Antibody; Anti-Lal Antibody; Anti-Lip-1 Antibody; Anti-Lip1 Antibody; anti-LIPA antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Mouse LIPA
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-LIPA antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:500-1:2000
Immunogen
A synthetic peptide corresponding to the center region of the Mouse LIPA
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Mouse LIPA, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of mouse LIPA in mouse liver with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of mouse LIPA in mouse liver with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-LIPA antibody
LIPA (Lipase A, Lysosomal Acid Type) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). LIPA is involved in the hydrolysis of triglycerides (TGs) and cholesteryl esters (CEs) delivered to lysosomes. It is broadly expressed in the spleen, small intestine, and other tissues. LIPA deficiency in the human causes two distinct phenotypes characterized by intracellular storage of CE and derangements in the control of cholesterol production, namely the Wolman disease (WD) and the CE storage disease (CESD). Loss of LIPA activity leads to diseases such as Wolman's Disease and Cholesterol Ester Storage Disease.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45,325 Da
NCBI Official Full Name
lysosomal acid lipase/cholesteryl ester hydrolase
NCBI Official Synonym Full Names
lysosomal acid lipase A
NCBI Official Symbol
Lipa
NCBI Official Synonym Symbols
Lal; Lip1; Lip-1; AA960673
NCBI Protein Information
lysosomal acid lipase/cholesteryl ester hydrolase
UniProt Protein Name
Lysosomal acid lipase/cholesteryl ester hydrolase
Protein Family
UniProt Gene Name
Lipa
UniProt Synonym Gene Names
Lip1; Acid cholesteryl ester hydrolase; LAL
Uniprot Description
Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation ().
Research Articles on LIPA
Similar Products
Product Notes
The LIPA lipa (Catalog #AAA8103752) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-LIPA Antibody, Rabbit Polyclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LIPA can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:500-1:2000. Researchers should empirically determine the suitability of the LIPA lipa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LIPA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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