Rabbit anti-Human KRT7 Polyclonal Antibody | anti-KRT7 antibody

KRT7 Antibody

Cat. Num. AAA7132844

• Gene Names: KRT7; K7; CK7; SCL; K2C7
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: KRT7; Polyclonal Antibody; KRT7 Antibody; Keratin type II cytoskeletal 7; Cytokeratin-7; CK-7; K7; Sarcolectin; anti-KRT7 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: Liquid; Rabbit IgG In Phosphate Buffered Saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol.

• Applicable Applications for anti-KRT7 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: WB: 1:500-1:3000; IHC: 1:50-1:100; IF: 1:100-1:500
• Immunogen: Synthesized peptide derived from human Keratin 7.
• Immunogen Species: Human
• Conjugate: Non-conjugated
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Keratin 7 antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of HepG2 cells, using Keratin 7 antibody.)

Western Blot (WB)

(Western blot analysis of extracts from HepG2 cells, using Keratin 7 antibody.)

Western Blot (WB)

(Western blot analysis of extracts from Hela cells (Lane 2) and HepG2 cells (Lane 3), using Keratin 7 antiobdy. The lane on the left is treated with synthesized peptide.)

Product Categories/Family for anti-KRT7 antibody

Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 67782365
• NCBI GeneID: 3855
• NCBI Accession #: NP_005547.3
• NCBI GenBank Nucleotide #: NM_005556.3
• UniProt Accession #: P08729; Q92676; Q9BUD8; Q9Y3R7
• Molecular Weight: 51,386 Da
• NCBI Official Full Name: keratin, type II cytoskeletal 7
• NCBI Official Synonym Full Names: keratin 7
• NCBI Official Symbol: KRT7
• NCBI Official Synonym Symbols: K7; CK7; SCL; K2C7
• NCBI Protein Information: keratin, type II cytoskeletal 7; CK-7; keratin-7; sarcolectin; cytokeratin 7; cytokeratin-7; type-II keratin Kb7; type II mesothelial keratin K7; keratin, 55K type II cytoskeletal; keratin, simple epithelial type I, K7
• UniProt Protein Name: Keratin, type II cytoskeletal 7
• Protein Family: Keratin
• UniProt Gene Name: KRT7
• UniProt Synonym Gene Names: SCL; CK-7; K7
• UniProt Entry Name: K2C7_HUMAN

NCBI Description

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]

Uniprot Description

K7: a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Phosphorylation of keratins at specific sites affects their organization, assembly dynamics, and their interaction with signaling molecules. Specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: cytoplasm; keratin filament; intermediate filament; nucleus

Molecular Function: protein binding; structural molecule activity

Biological Process: viral reproduction