Rabbit KLK12 Polyclonal Antibody | anti-KLK12 antibody
KLK12 Polyclonal Antibody
This antibody recognizes the gene product hk12 of human KLK12 (also known as KLK-L5), one of the many kallikrein serine proteases associated with carcinogenesis. KLK12 is expressed in salivary glands, stomach, uterus, trachea, prostate, thymus, lung, colon, brain, breast, and thyroid and is up-regulated by androgens, progestins, and estrogens
NCBI and Uniprot Product Information
NCBI Description
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq]
Uniprot Description
KLK12: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Protein type: Protease; Secreted, signal peptide; Secreted; EC 3.4.21.-
Chromosomal Location of Human Ortholog: 19q13.33
Cellular Component: extracellular space
Molecular Function: peptidase activity; serine-type peptidase activity; serine-type endopeptidase activity
Biological Process: proteolysis
Research Articles on KLK12
Similar Products
Product Notes
The KLK12 klk12 (Catalog #AAA194278) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's KLK12 can be used in a range of immunoassay formats including, but not limited to, Immunoblot. Immunoblotting: use at 1:500-1:1,000 dilution. A band of approximately 27 kD is detected. Researchers should empirically determine the suitability of the KLK12 klk12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLK12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
