Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using KLF3 antibody.)
Rabbit anti-Human KLF3 Polyclonal Antibody | anti-KLF3 antibody
KLF3 Polyclonal Antibody
Gene Names
KLF3; BKLF
Reactivity
Human
Applications
Western Blot, Immunofluorescence
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
KLF3; Polyclonal Antibody; KLF3 Polyclonal Antibody; Krueppel-like factor 3; Basic krueppel-like factor; CACCC-box-binding protein BKLF; TEF-2; BKLF; anti-KLF3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
KLF3 polyclonal antibody detects endogenous levels of KLF3 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
345
Applicable Applications for anti-KLF3 antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes
WB: 1:500-1:2000
IF: 1:50-1:100
IF: 1:50-1:100
Immunogen
Recombinant full length Human KLF3.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using KLF3 antibody.)
Western Blot (WB)
(Western Blot analysis of extracts of various cell lines, using KLF3 antibody.)
Immunofluorescence (IF)
(Immunofluorescence analysis of A549 cell using KLF3 antibody.)
Immunofluorescence (IF)
(Immunofluorescence analysis of A549 cell using KLF3 antibody.)
Related Product Information for anti-KLF3 antibody
Krueppel-like factors (KLFs) comprise a family of evolutionarily conserved zinc finger-containing transcription factors with diverse regulatory functions in cell growth, proliferation, differentiation and embryogenesis. Individual members of the Sp1-like/KLF family can function either as activators or repressors, depending on which promoter they bind and the coregulators with which they interact. KLF6, also designated Zf9 or CPBP (core promoter-binding protein), and KLF3 are Krüppel-like zinc finger containing transcription factors. KLF6 is rapidly induced during hepatic stellate cell activation and transactivates a reporter gene driven by the collagen I promoter, suggesting KLF6 plays a role in the response to tissue injury. KLF3 may play a role in hematopoiesis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 39kDa
NCBI Official Full Name
Krueppel-like factor 3
NCBI Official Synonym Full Names
Kruppel like factor 3
NCBI Official Symbol
KLF3
NCBI Official Synonym Symbols
BKLF
NCBI Protein Information
Krueppel-like factor 3
UniProt Protein Name
Krueppel-like factor 3
Protein Family
UniProt Gene Name
KLF3
UniProt Synonym Gene Names
BKLF
UniProt Entry Name
KLF3_HUMAN
Uniprot Description
KLF3: Binds to the CACCC box of erythroid cell-expressed genes. May play a role in hematopoiesis. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding; Transcription factor; C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 4p14
Cellular Component: nucleus
Molecular Function: DNA binding; metal ion binding; transcription factor activity
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; multicellular organismal development
Research Articles on KLF3
Similar Products
Product Notes
The KLF3 klf3 (Catalog #AAA3011995) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KLF3 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KLF3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). WB: 1:500-1:2000 IF: 1:50-1:100. Researchers should empirically determine the suitability of the KLF3 klf3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KLF3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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