Rabbit anti-Human KHDRBS1 Polyclonal Antibody | anti-KHDRBS1 antibody

KHDRBS1 Antibody

Cat. Num. AAA9418552

• Gene Names: KHDRBS1; p62; p68; Sam68
• Reactivity: Human
• Applications: Western Blot
• Synonyms: KHDRBS1; Polyclonal Antibody; KHDRBS1 Antibody; p62; Sam68; p68; anti-KHDRBS1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: KHDRBS1 Antibody detects endogenous levels of total KHDRBS1
• Form/Format: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0mg/mL (varies by lot)
• Sequence Length: 404

• Applicable Applications for anti-KHDRBS1 antibody: Western Blot (WB)
• Application Notes: Western Blot: 1:1000-3000
• Immunogen: A synthesized peptide derived from human KHDRBS1
• Immunogen Type: Peptide
• Preparation and Storage: Store at -20 degree C

Western Blot (WB)

(Western blot analysis KHDRBS1 using LOVO whole cell lysates)

Product Categories/Family for anti-KHDRBS1 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 428673536
• NCBI GeneID: 10657
• NCBI Accession #: NP_001258807.1
• NCBI GenBank Nucleotide #: NM_001271878.1
• UniProt Accession #: Q07666; Q6PJX7; Q8NB97; Q99760; D3DPP3
• Molecular Weight: 44,027 Da
• NCBI Official Full Name: KH domain-containing, RNA-binding, signal transduction-associated protein 1 isoform 2
• NCBI Official Synonym Full Names: KH RNA binding domain containing, signal transduction associated 1
• NCBI Official Symbol: KHDRBS1
• NCBI Official Synonym Symbols: p62; p68; Sam68
• NCBI Protein Information: KH domain-containing, RNA-binding, signal transduction-associated protein 1
• UniProt Protein Name: KH domain-containing, RNA-binding, signal transduction-associated protein 1
• Protein Family: KH domain-containing, RNA-binding, signal transduction-associated protein
• UniProt Gene Name: KHDRBS1
• UniProt Synonym Gene Names: Sam68
• UniProt Entry Name: KHDR1_HUMAN

NCBI Description

This gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

Uniprot Description

KHDRBS1: a nuclear RNA-binding protein. May be involved in slicing and mRNA transport. Associates with src in mitosis. Binds to RNA via a heteronuclear ribonucleoprotein K homology domain. Exerts functionally separable effects on cell proliferation and survival, dependent on its ability to bind specifically to RNA.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 1p32

Cellular Component: cytosol; membrane; nucleoplasm; nucleus

Molecular Function: DNA binding; identical protein binding; poly(A) binding; poly(U) binding; protein binding; RNA binding; SH3/SH2 adaptor activity

Biological Process: cell cycle arrest; cell proliferation; cell surface receptor linked signal transduction; G2/M transition of mitotic cell cycle; negative regulation of transcription, DNA-dependent; positive regulation of RNA export from nucleus; positive regulation of translational initiation; regulation of protein stability; regulation of RNA export from nucleus; signal transduction