Rabbit KCTD15 Polyclonal Antibody | anti-KCTD15 antibody

KCTD15 Antibody

Cat. Num. AAA150095

• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
• Purity: KCTD15 Antibody is affinity chromatography purified via peptide column.
• Synonyms: KCTD15; Polyclonal Antibody; KCTD15 Antibody; Potassium channel tetramerization domain-containing protein 15; potassium channel tetramerisation domain containing 15; anti-KCTD15 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: KCTD15 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 283

• Applicable Applications for anti-KCTD15 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Application Notes: KCTD15 antibody can be used for detection of KCTD15 by Western blot at 0.5 - 1 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL.
• Conjugate: Unconjugated
• Immunogen: KCTD15 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human KCTD15.
• Buffer: KCTD15 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: KCTD15 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of KCTD15 in HeLa cell lysate with KCTD15 antibody at 1μg/ml in (A) the absence and (B) the presence of blocking buffer.)

Immunohistochemistry (IHC)

(Immunohistochemistry of KCTD15 in human spleen tissue with KCTD15 antibody at 2.5 μg/mL.)

Immunofluorescence (IF)

(Immunofluorescence of KCTD15 in human spleen tissue with KCTD15 antibody at 20 μg/mL.)

Related Product Information for anti-KCTD15 antibody

KCTD15 Antibody: Childhood and adult obesity in the United States and to a lesser extent the rest of the world has increased dramatically over the past decade. Both environmental and genetic factors are involved in the onset and progression of weight gain. Recently, the potassium channel KCTD15 was identified as a genetic loci associated with higher than normal body mass index (BMI) in humans along with genes such as GNPDA2, MTCH2, FTO, and TMEM18. Further studies on single nucleotide polymorphisms (SNPs) in non-diabetic and diabetic patients showed that FTO was most strongly associated with obesity while MTCH2 and GNPDA2 were still significantly associated with higher than normal BMI levels. At least two isoforms of KCTD15 are known to exist.

NCBI and Uniprot Product Information

• NCBI GI #: 74732704
• NCBI GeneID: 79047
• UniProt Accession #: Q96SI1; Q9BVI6; A8K600
• Molecular Weight: 26,476 Da
• NCBI Official Full Name: BTB/POZ domain-containing protein KCTD15
• NCBI Official Synonym Full Names: potassium channel tetramerization domain containing 15
• NCBI Official Symbol: KCTD15
• NCBI Protein Information: BTB/POZ domain-containing protein KCTD15; potassium channel tetramerisation domain containing 15; potassium channel tetramerization domain-containing protein 15
• UniProt Protein Name: BTB/POZ domain-containing protein KCTD15
• Protein Family: BTB/POZ domain-containing protein
• UniProt Gene Name: KCTD15
• UniProt Entry Name: KCD15_HUMAN

Uniprot Description

KCTD15: 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 19q13.11

Biological Process: multicellular organismal development; protein homooligomerization