Western Blot (WB)
(Western Blot analysis in K562 cell line lysates (35ug/lane) usingMBS647073. This demonstrates that MBS647073 detected the KCNJ6 protein (arrow).)
Rabbit anti-Human KCNJ6 Polyclonal Antibody | anti-KCNJ6 antibody
KCNJ6, ID (KCNJ6, GIRK2, KATP2, KCNJ7, G protein-activated inward rectifier potassium channel 2, BIR1, Inward rectifier K(+) channel Kir3.2, KATP-2, Potassium channel, inwardly rectifying subfamily J member 6) (MaxLight 750)
Western Blot (WB)
(Western Blot analysis in K562 cell line lysates (35ug/lane) usingMBS647073. This demonstrates that MBS647073 detected the KCNJ6 protein (arrow).)
Western Blot (WB)
(Western Blot analysis in K562 cell line lysates (35ug/lane) usingMBS647073. This demonstrates that MBS647073 detected the KCNJ6 protein (arrow).)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue using MBS647073 followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of MBS647073 for immunohistochemistry.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue using MBS647073 followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of MBS647073 for immunohistochemistry.)
Flow Cytometry (FC/FACS)
(Flow Cytometric analysis of K562 cells using MBS647073 (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(Flow Cytometric analysis of K562 cells using MBS647073 (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the G protein-coupled inwardly-rectifying potassium channel family of inward rectifier potassium channels. This type of potassium channel allows a greater flow of potassium into the cell than out of it. These proteins modulate many physiological processes, including heart rate in cardiac cells and circuit activity in neuronal cells, through G-protein coupled receptor stimulation. Mutations in this gene are associated with Keppen-Lubinsky Syndrome, a rare condition characterized by severe developmental delay, facial dysmorphism, and intellectual disability. [provided by RefSeq, Apr 2015]
Uniprot Description
This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Research Articles on KCNJ6
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Product Notes
The KCNJ6 kcnj6 (Catalog #AAA6312586) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KCNJ6, ID (KCNJ6, GIRK2, KATP2, KCNJ7, G protein-activated inward rectifier potassium channel 2, BIR1, Inward rectifier K(+) channel Kir3.2, KATP-2, Potassium channel, inwardly rectifying subfamily J member 6) (MaxLight 750) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KCNJ6 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB), Flow Cytometry (FC/FACS), FLISA. Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the KCNJ6 kcnj6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCNJ6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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