Western Blot (WB)
(KCNAB3 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the KCNAB3 antibody detected the KCNAB3 protein (arrow).)
Rabbit anti-Human KCNAB3 Polyclonal Antibody | anti-KCNAB3 antibody
KCNAB3 Antibody (Center)
Gene Names
KCNAB3; AKR6A9; KCNA3B; KCNA3.1B; KV-BETA-3
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
KCNAB3; Polyclonal Antibody; KCNAB3 Antibody (Center); Voltage-gated potassium channel subunit beta-3; K(+) channel subunit beta-3; Kv-beta-3; KCNA3B; anti-KCNAB3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This KCNAB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-204 amino acids from the Central region of human KCNAB3.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.35 (varies by lot)
Sequence Positions
176-204
Sequence Length
404
Applicable Applications for anti-KCNAB3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(KCNAB3 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the KCNAB3 antibody detected the KCNAB3 protein (arrow).)
Western Blot (WB)
(KCNAB3 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the KCNAB3 antibody detected the KCNAB3 protein (arrow).)
Related Product Information for anti-KCNAB3 antibody
Voltage-gated potassium (Kv) channels represent the most
complex class of voltage-gated ion channels from both functional
and structural standpoints. Their diverse functions include
regulating neurotransmitter release, heart rate, insulin secretion,
neuronal excitability, epithelial electrolyte transport, smooth
muscle contraction, and cell volume. Four sequence-related
potassium channel genes - shaker, shaw, shab, and shal - have been
identified in Drosophila, and each has been shown to have human
homolog(s). This gene encodes a member of the potassium channel,
voltage-gated, shaker-related subfamily. This member is one of the
beta subunits, which are auxiliary proteins associating with
functional Kv-alpha subunits. This member and the KCNA5 gene
product assemble into a heteromultimeric A-type channel that
inactivates completely and is significantly faster than other
A-type Kv channels.
complex class of voltage-gated ion channels from both functional
and structural standpoints. Their diverse functions include
regulating neurotransmitter release, heart rate, insulin secretion,
neuronal excitability, epithelial electrolyte transport, smooth
muscle contraction, and cell volume. Four sequence-related
potassium channel genes - shaker, shaw, shab, and shal - have been
identified in Drosophila, and each has been shown to have human
homolog(s). This gene encodes a member of the potassium channel,
voltage-gated, shaker-related subfamily. This member is one of the
beta subunits, which are auxiliary proteins associating with
functional Kv-alpha subunits. This member and the KCNA5 gene
product assemble into a heteromultimeric A-type channel that
inactivates completely and is significantly faster than other
A-type Kv channels.
Product Categories/Family for anti-KCNAB3 antibody
References
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Leicher, T., et al. J. Biol. Chem. 273(52):35095-35101(1998)
McCormack, K., et al. FEBS Lett. 370 (1-2), 32-36 (1995) :
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Leicher, T., et al. J. Biol. Chem. 273(52):35095-35101(1998)
McCormack, K., et al. FEBS Lett. 370 (1-2), 32-36 (1995) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
43670
NCBI Official Full Name
voltage-gated potassium channel subunit beta-3
NCBI Official Synonym Full Names
potassium channel, voltage gated subfamily A regulatory beta subunit 3
NCBI Official Symbol
KCNAB3
NCBI Official Synonym Symbols
AKR6A9; KCNA3B; KCNA3.1B; KV-BETA-3
NCBI Protein Information
voltage-gated potassium channel subunit beta-3
UniProt Protein Name
Voltage-gated potassium channel subunit beta-3
Protein Family
UniProt Gene Name
KCNAB3
UniProt Synonym Gene Names
KCNA3B
UniProt Entry Name
KCAB3_HUMAN
NCBI Description
This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. The encoded protein is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. The encoded protein forms a heterodimer with the potassium voltage-gated channel, shaker-related subfamily, member 5 gene product and regulates the activity of the alpha subunit. [provided by RefSeq, May 2012]
Uniprot Description
KCNAB3: Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5. Belongs to the shaker potassium channel beta subunit family.
Protein type: Channel, potassium
Chromosomal Location of Human Ortholog: 17p13.1
Cellular Component: cytoplasm; integral to membrane; plasma membrane
Molecular Function: voltage-gated potassium channel activity; potassium channel regulator activity
Biological Process: synaptic transmission; potassium ion transport
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Product Notes
The KCNAB3 kcnab3 (Catalog #AAA9205372) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 176-204. The KCNAB3 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KCNAB3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the KCNAB3 kcnab3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCNAB3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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