Western Blot (WB)
(KAZ Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the KAZ antibody detected the KAZ protein (arrow).)
Rabbit anti-Human KAZ Polyclonal Antibody | anti-KAZ antibody
KAZ, CT (KAZN, KAZ, KIAA1026, Kazrin) (PE)
Gene Names
KAZN; KAZ
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
KAZ; Polyclonal Antibody; CT (KAZN; KIAA1026; Kazrin) (PE); KAZN; Kazrin; anti-KAZ antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Applicable Applications for anti-KAZ antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
KAZ antibody is generated from rabbits immunized with a KLH conjugated synthetic between 710-739 amino acids selected from the C-terminal region of human KAZ.
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(KAZ Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the KAZ antibody detected the KAZ protein (arrow).)
Western Blot (WB)
(KAZ Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the KAZ antibody detected the KAZ protein (arrow).)
Related Product Information for anti-KAZ antibody
Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known.
Product Categories/Family for anti-KAZ antibody
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Nachat, R., et al. J. Cell. Sci. 122 (PT 22), 4035-4041 (2009): Wang, Q., et al. Acta Biochim. Biophys. Sin. (Shanghai) 41(9):763-772(2009). Sevilla, L.M., et al. J. Cell. Sci. 121 (PT 21), 3561-3569 (2008): Uhl, G.R., et al. Arch. Gen. Psychiatry 65(6):683-693(2008).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
46,250 Da
NCBI Official Full Name
kazrin isoform C
NCBI Official Synonym Full Names
kazrin, periplakin interacting protein
NCBI Official Symbol
KAZN
NCBI Official Synonym Symbols
KAZ
NCBI Protein Information
kazrin
UniProt Protein Name
Kazrin
Protein Family
UniProt Gene Name
KAZN
UniProt Synonym Gene Names
KAZ; KIAA1026
UniProt Entry Name
KAZRN_HUMAN
NCBI Description
This gene encodes a protein that plays a role in desmosome assembly, cell adhesion, cytoskeletal organization, and epidermal differentiation. This protein co-localizes with desmoplakin and the cytolinker protein periplakin. In general, this protein localizes to the nucleus, desmosomes, cell membrane, and cortical actin-based structures. Some isoforms of this protein also associate with microtubules. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity has not been verified. [provided by RefSeq, Aug 2011]
Research Articles on KAZ
Similar Products
Product Notes
The KAZ kazn (Catalog #AAA6312147) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KAZ, CT (KAZN, KAZ, KIAA1026, Kazrin) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KAZ can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the KAZ kazn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KAZ, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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