Immunohistochemistry (IHC)
(Anti-Kallistatin antibody, MBS175544, IHC(P)IHC(P): Human Liver Cancer Tissue )
Rabbit anti-Human Kallistatin Polyclonal Antibody | anti-SERPINA4 antibody
Anti-Kallistatin antibody
Gene Names
SERPINA4; KAL; KST; PI4; KLST; PI-4; kallistatin
Reactivity
Human
Applications
Western Blot, Immunohistochemistry
Purity
Immunogen affinity purified.
Synonyms
Kallistatin; Polyclonal Antibody; Anti-Kallistatin antibody; serpin peptidase inhibitor; clade A(alpha-1 antiproteinase; antitrypsin); member 4; KAIN_HUMAN antibody; KAL antibody; Kallikrein binding protein antibody; Kallikrein inhibitor antibody; Kallistatin antibody; KBP antibody; KLST antibody; KST antibody; MGC108582 antibody; Peptidase inhibitor 4 antibody; PI-4 antibody; PI4 antibody; Protease inhibitor 4(kallistatin) antibody; Protease inhibitor 4 antibody; Serine(or cysteine) proteinase inhibitor; clade A(alpha 1 antiproteinase; member 4 antibody; Serpin A4 antibody; Serpin peptidase inhibitor clade A member 4 antibody; Serpin peptidase inhibitor; SERPINA4 antibody; anti-SERPINA4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
427
Applicable Applications for anti-SERPINA4 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Kallistatin (384-401aa AIKFFSAQTNRHILRFNR).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Immunohistochemistry (IHC)
(Anti-Kallistatin antibody, MBS175544, IHC(P)IHC(P): Human Liver Cancer Tissue )
Immunohistochemistry (IHC)
(Anti-Kallistatin antibody, MBS175544, IHC(P)IHC(P): Human Liver Cancer Tissue )
Western Blot (WB)
(Anti-Kallistatin antibody, MBS175544, Western blottingLane 1: SMMC Cell LysateLane 2: COLO320 Cell LysateLane 3: JURKAT Cell Lysate )
Western Blot (WB)
(Anti-Kallistatin antibody, MBS175544, Western blottingLane 1: SMMC Cell LysateLane 2: COLO320 Cell LysateLane 3: JURKAT Cell Lysate )
Western Blot (WB)
(Anti-Kallistatin antibody, MBS175544, Western blottingLane 1: HELA Cell LysateLane 2: SKOV Cell Lysate )
Western Blot (WB)
(Anti-Kallistatin antibody, MBS175544, Western blottingLane 1: HELA Cell LysateLane 2: SKOV Cell Lysate )
Related Product Information for anti-SERPINA4 antibody
Description: Rabbit IgG polyclonal antibody for Kallistatin(SERPINA4) detection. Tested with WB, IHC-P in Human.
Background: Serpina 4, also called Kallistatin, PI4 or TISSUE KALLIKREIN INHIBITOR, is a protein that in humans is encoded by the SERPINA4 gene. The serpina4 is a member of the serpin superfamily and represents a major inhibitor of human tissue kallikrein in the circulation. The SERPINA4 gene is localized to 14q32.13. The translated amino acid sequence of serpina4 matches the protein sequence and shares 44 to 46% sequence identity with other serpin family members. Kallistatin is a serine proteinase inhibitor(serpin) and a heparin-binding protein. It is localized in vascular smooth muscle cells and endothelial cells of blood vessels, suggesting that it may be involved in the regulation of vascular function. And serpina4 also plays a role in neointima hyperplasia.
Background: Serpina 4, also called Kallistatin, PI4 or TISSUE KALLIKREIN INHIBITOR, is a protein that in humans is encoded by the SERPINA4 gene. The serpina4 is a member of the serpin superfamily and represents a major inhibitor of human tissue kallikrein in the circulation. The SERPINA4 gene is localized to 14q32.13. The translated amino acid sequence of serpina4 matches the protein sequence and shares 44 to 46% sequence identity with other serpin family members. Kallistatin is a serine proteinase inhibitor(serpin) and a heparin-binding protein. It is localized in vascular smooth muscle cells and endothelial cells of blood vessels, suggesting that it may be involved in the regulation of vascular function. And serpina4 also plays a role in neointima hyperplasia.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
48,542 Da
NCBI Official Full Name
Kallistatin
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
NCBI Official Symbol
SERPINA4
NCBI Official Synonym Symbols
KAL; KST; PI4; KLST; PI-4; kallistatin
NCBI Protein Information
kallistatin; serpin A4; kallikrein inhibitor; peptidase inhibitor 4; protease inhibitor 4 (kallistatin); serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
UniProt Protein Name
Kallistatin
Protein Family
UniProt Gene Name
SERPINA4
UniProt Synonym Gene Names
KST; PI4; PI-4
UniProt Entry Name
KAIN_HUMAN
Uniprot Description
SERPINA4: Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein. Belongs to the serpin family.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 14q32.13
Cellular Component: extracellular space
Molecular Function: serine-type endopeptidase inhibitor activity
Research Articles on SERPINA4
Similar Products
Product Notes
The SERPINA4 serpina4 (Catalog #AAA175544) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Kallistatin antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Kallistatin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the SERPINA4 serpina4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Kallistatin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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