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Immunohistochemistry (IHC) (Anti-JPH4 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Rabbit JPH4 Polyclonal Antibody | anti-JPH4 antibody

Rabbit Polyclonal to Human JPH4

Gene Names
JPH4; JP4; JPHL1
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Immunoaffinity Purified
Synonyms
JPH4; Polyclonal Antibody; Rabbit Polyclonal to Human JPH4; Anti-JPH4 Antibody (Internal) IHC-plus; JP-4; Junctophilin 4; JP4; JPHL1; Junctophilin-4; KIAA1831; Junctophilin-like 1 protein; Junctophilin like 1; Human JPH4; anti-JPH4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS containing 0.02% sodium azide
Concentration
1 mg/ml (varies by lot)
Sequence Length
628
Applicable Applications for anti-JPH4 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes
ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml)
Target Species
Human
Immunogen Description
A 17 amino acid peptide near the center of human JPH4.
Immunogen Type
Synthetic peptide
Immunogen
JPH4 antibody was raised against a 17 amino acid peptide near the center of human JPH4.
Antigen Modification
Internal
Preparation and Storage
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-JPH4 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-JPH4 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC)

(Anti-JPH4 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-JPH4 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC)

(Anti-JPH4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC) (Anti-JPH4 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Western Blot (WB)

(Western blot of JPH4 in mouse brain tissue lysate with JPH4 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.)

Western Blot (WB) (Western blot of JPH4 in mouse brain tissue lysate with JPH4 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
65,861 Da
NCBI Official Full Name
junctophilin-4
NCBI Official Synonym Full Names
junctophilin 4
NCBI Official Symbol
JPH4
NCBI Official Synonym Symbols
JP4; JPHL1
NCBI Protein Information
junctophilin-4; JP-4; junctophilin like 1; junctophilin-like 1 protein
UniProt Protein Name
Junctophilin-4
Protein Family
UniProt Gene Name
JPH4
UniProt Synonym Gene Names
JPHL1; KIAA1831; JP-4
UniProt Entry Name
JPH4_HUMAN

NCBI Description

This gene encodes a member of the junctophilin family of transmembrane proteins that are involved in the formation of the junctional membrane complexes between the plasma membrane and the endoplasmic/sarcoplasmic reticulum in excitable cells. The encoded protein contains a conserved N-terminal repeat region called the membrane occupation and recognition nexus sequence that is found in other members of the junctophilin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]

Uniprot Description

JPH4: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH4 is brain- specific and appears to have an active role in certain neurons involved in motor coordination and memory. Belongs to the junctophilin family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 14q11

Cellular Component: smooth endoplasmic reticulum; integral to membrane; plasma membrane; dendritic shaft

Biological Process: regulation of synaptic plasticity; learning; neuromuscular process controlling balance

Research Articles on JPH4

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Product Notes

The JPH4 jph4 (Catalog #AAA242709) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human JPH4 reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's JPH4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA). ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml). Researchers should empirically determine the suitability of the JPH4 jph4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "JPH4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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