Western Blot (WB)
(Western blot analysis of ITGB1BP3 Antibody (N-term) in K562 cell line lysates (35ug/lane). ITGB1BP3 (arrow) was detected using the purified Pab.)
Rabbit anti-Human ITGB1BP3 Polyclonal Antibody | anti-ITGB1BP3 antibody
ITGB1BP3, NT (Nicotinamide Riboside Kinase 2, NmR-K 2, NRK 2, Ribosylnicotinamide Kinase 2, RNK 2, Nicotinic Acid Riboside Kinase 2, Ribosylnicotinic Acid Kinase 2, Integrin beta-1-binding Protein 3, Muscle Integrin-binding Protein, MIBP, NRK2)
Purified by ammonium sulfate precipitation.
Purified by ammonium sulfate precipitation.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:10-1:50
Western Blot (WB)
(Western blot analysis of ITGB1BP3 Antibody (N-term) in K562 cell line lysates (35ug/lane). ITGB1BP3 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of ITGB1BP3 Antibody (N-term) in K562 cell line lysates (35ug/lane). ITGB1BP3 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with ITGB1BP3 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with ITGB1BP3 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
Uniprot Description
ITGB1BP3: an enzyme that catalyzes the phosphorylation of nicotinamide riboside and nicotinic acid riboside to form nicotinamide mononucleotide and nicotinic acid mononucleotide. Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Interacts with ITGB1 alone or when associated with alpha-7, but not with alpha-5. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. Predominantly expressed in skeletal muscle and, at a much lower level, in the heart (at protein level). No expression in brain, kidney, liver, lung, pancreas nor placenta. May play a role in the regulation of terminal myogenesis. Two alternatively spliced human isoforms have been described.
Protein type: EC 2.7.1.173; Cell adhesion; Cell development/differentiation; Kinase, other; EC 2.7.1.22
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: intracellular
Molecular Function: protein binding; ribosylnicotinamide kinase activity; metal ion binding; ATP binding
Biological Process: NAD biosynthetic process; negative regulation of myoblast differentiation; phosphorylation
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Product Notes
The ITGB1BP3 nmrk2 (Catalog #AAA629990) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ITGB1BP3, NT (Nicotinamide Riboside Kinase 2, NmR-K 2, NRK 2, Ribosylnicotinamide Kinase 2, RNK 2, Nicotinic Acid Riboside Kinase 2, Ribosylnicotinic Acid Kinase 2, Integrin beta-1-binding Protein 3, Muscle Integrin-binding Protein, MIBP, NRK2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ITGB1BP3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC). Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Dilution: ELISA: 1:1,000 Western Blot: 1:50-1:100 Immunohistochemistry: 1:10-1:50. Researchers should empirically determine the suitability of the ITGB1BP3 nmrk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ITGB1BP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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