Western Blot (WB)
(Mouse Irak4 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the Irak4 antibody detected the Irak4 protein (arrow).)
Rabbit anti-Human Irak4 Polyclonal Antibody | anti-Irak4 antibody
Mouse Irak4 Antibody (C-term)
Western Blot (WB)
(Mouse Irak4 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the Irak4 antibody detected the Irak4 protein (arrow).)
Western Blot (WB)
(Mouse Irak4 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the Irak4 antibody detected the Irak4 protein (arrow).)
Maekawa, Y., et al. Circulation 120(14):1401-1414(2009)
Bauernfeind, F.G., et al. J. Immunol. 183(2):787-791(2009)
Staschke, K.A., et al. J. Immunol. 183(1):568-577(2009)
Koziczak-Holbro, M., et al. Arthritis Rheum. 60(6):1661-1671(2009)
NCBI and Uniprot Product Information
Uniprot Description
IRAK4: a TKL kinase of the IRAK family. The interleukin-1 receptor-associated kinases are important mediators in the signal transduction of Toll-like receptor and IL1R family members, collectively referred to as TIRs.
Protein type: EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Protein kinase, TKL; Kinase, protein; TKL group; IRAK family
Cellular Component: extracellular space; cytoplasm; plasma membrane; intracellular; nucleus
Molecular Function: transferase activity; protein serine/threonine kinase activity; protein binding; interleukin-1 receptor binding; transferase activity, transferring phosphorus-containing groups; nucleotide binding; magnesium ion binding; kinase activity; ATP binding; protein kinase activity
Biological Process: positive regulation of I-kappaB kinase/NF-kappaB cascade; immune system process; cytokine and chemokine mediated signaling pathway; positive regulation of smooth muscle cell proliferation; innate immune response; JNK cascade; cytokine production; signal transduction; phosphorylation; protein amino acid phosphorylation
Research Articles on Irak4
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Product Notes
The Irak4 irak4 (Catalog #AAA9213464) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 422-449. The Mouse Irak4 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Irak4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Irak4 irak4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Irak4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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