Western Blot (WB)
(Western blot analysis of the lysates from HepG2 cells using DNL1 antibody.)
Rabbit anti-Human DNL1 Polyclonal Antibody | anti-DNL1 antibody
DNL1 Antibody
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Synonyms
DNL1; Polyclonal Antibody; DNL1 Antibody; DNA ligase I; LIG-1; Polydeoxyribonucleotide synthase [ATP]; anti-DNL1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
DNL1 Antibody detects endogenous levels of DNL1.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
888
Applicable Applications for anti-DNL1 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:10000
IHC: 1:50~1:100
ELISA: 1:10000
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human DNL1.
Immunogen Range
90-139
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Western Blot (WB)
(Western blot analysis of the lysates from HepG2 cells using DNL1 antibody.)
Western Blot (WB)
(Western blot analysis of the lysates from HepG2 cells using DNL1 antibody.)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
101 kDa
NCBI Official Full Name
DNA ligase 1 isoform 1
NCBI Official Synonym Full Names
DNA ligase 1
NCBI Official Symbol
LIG1
NCBI Protein Information
DNA ligase 1
UniProt Protein Name
DNA ligase 1
UniProt Gene Name
LIG1
NCBI Description
This gene encodes a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Uniprot Description
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
Research Articles on DNL1
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Product Notes
The DNL1 lig1 (Catalog #AAA9509399) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DNL1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DNL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000. Researchers should empirically determine the suitability of the DNL1 lig1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DNL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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