Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded section of Human Uroepithelium Cancer Tissue)
Rabbit Integrin beta 2 Polyclonal Antibody
Integrin beta 2 antibody
Applications
Western Blot, Immunohistochemistry
Purity
Integrin beta 2 antibody was purified by affinity chromatography
Synonyms
Integrin beta 2; Polyclonal Antibody; Integrin beta 2 antibody; Polyclonal Integrin beta 2; Anti-Integrin beta 2; LFA1; CD18; Integrin beta -2; MAC1; anti-Integrin beta 2 antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Integrin beta 2 antibody was purified by affinity chromatography
Form/Format
Supplied in lyophilized form
Applicable Applications for anti-Integrin beta 2 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin
Application Notes
Optimal conditions to be determined by the end user
Biological Significance
The beta-2 integrin chain gene is designated ITGB2 and the leukocyte antigen has been designated CD18. The 3 alpha integrin chains associated individually with the beta-2 chain as a heterodimer have gene designations of ITGAL, ITGAM, and ITGAX, and leukocyte antigen designations of CD11A, CD11B, and CD11C, respectively.The expression of CD18 was increased in lymphoblastoid cells from persons with Down syndrome, consistent with the location of the gene on chromosome 211.The ITGB2 gene spans approximately 40 kb and contains 16 exons and all exon/intron boundaries conform to the GT/AG splicing consensus2. Furthermore, ITGB2 was constitutively clustered. Although it was expressed on the cell surface at normal levels and was capable of function following extracellular stimulation, it could not be activated via the ?inside-out? signaling pathways3.
Immunogen
Integrin beta 2 antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the N-terminal of human Integrin beta2, different from the related Rabbit sequence by five amino acids, as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage. For long term storage aliquot and store at -20 degree C, avoid repeated freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded section of Human Uroepithelium Cancer Tissue)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded section of Human Uroepithelium Cancer Tissue)
Related Product Information for anti-Integrin beta 2 antibody
Affinity purified Rabbit polyclonal Integrin beta 2 antibody
Product Categories/Family for anti-Integrin beta 2 antibody
Similar Products
Product Notes
The Integrin beta 2 (Catalog #AAA839369) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Integrin beta 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Optimal conditions to be determined by the end user. Researchers should empirically determine the suitability of the Integrin beta 2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Integrin beta 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
