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Immunohistochemistry (IHC) (Human Uterus, Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE))

Rabbit INHBB/Inhibin Beta B Polyclonal Antibody | anti-INHBB antibody

Anti-INHBB/Inhibin Beta B Antibody (Internal)

Reactivity
Human
Predicted: Chicken, Zebrafish, Pig, Mouse, Rat, Sheep, Bovine
Applications
Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
INHBB/Inhibin Beta B; Polyclonal Antibody; Anti-INHBB/Inhibin Beta B Antibody (Internal); Rabbit Polyclonal to Human INHBB/Inhibin Beta B; INHBB; Activin beta-B chain; Activin AB beta polypeptide; Inhibin; beta B; Inhibin Beta B; Inhibin beta B chain; beta-2; anti-INHBB antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Chicken, Zebrafish, Pig, Mouse, Rat, Sheep, Bovine
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of Inhibin beta B protein.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, pH 7.3, 0.01% sodium azide, 30% glycerol.
Sequence Length
407
Applicable Applications for anti-INHBB antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P: 1:100
WB: 1:500-1:1000
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the central region of human Inhibin beta B.
Conjugation
Unconjugated
Epitope
Internal
Preparation and Storage
Aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Human Uterus, Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Uterus, Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (WB)

(Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (WB) (Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Western blot analysis of Inhibin beta B expression in HeLa (A); mouse brain (B) whole cell lysates.)

Western Blot (WB) (Western blot analysis of Inhibin beta B expression in HeLa (A); mouse brain (B) whole cell lysates.)
Related Product Information for anti-INHBB antibody
The inhibin beta B subunit joins the alpha subunit to form a pituitaryFSH secretion inhibitor. Inhibin has been shown to regulate gonadalstromal cell proliferation negatively and to have tumour-suppressoractivity. In addition, serum levels of inhibin have been shown toreflect the size of granulosa-cell tumors and can the refore be used as amarker for primary as well as recurrent disease.
Product Categories/Family for anti-INHBB antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45,122 Da
NCBI Official Full Name
inhibin beta B chain preproprotein
NCBI Official Synonym Full Names
inhibin subunit beta B
NCBI Official Symbol
INHBB
NCBI Protein Information
inhibin beta B chain
UniProt Protein Name
Inhibin beta B chain
Protein Family
UniProt Gene Name
INHBB

NCBI Description

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. Polymorphisms near this gene are associated with pre-eclampsia in female human patients. [provided by RefSeq, Aug 2016]

Uniprot Description

Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

Research Articles on INHBB

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Product Notes

The INHBB inhbb (Catalog #AAA2401778) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-INHBB/Inhibin Beta B Antibody (Internal) reacts with Human Predicted: Chicken, Zebrafish, Pig, Mouse, Rat, Sheep, Bovine and may cross-react with other species as described in the data sheet. AAA Biotech's INHBB/Inhibin Beta B can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 1:100 WB: 1:500-1:1000. Researchers should empirically determine the suitability of the INHBB inhbb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "INHBB/Inhibin Beta B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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