Human A Disintegrin And Metalloprotease 12 (ADAM12) ELISA Kit | ADAM12 elisa kit

Human A Disintegrin And Metalloprotease 12 (ADAM12) ELISA Kit

Cat. Num. AAA450791

• Gene Names: ADAM12; MCMP; MLTN; CAR10; MLTNA; MCMPMltna; ADAM12-OT1
• Reactivity: Human
• Synonyms: A Disintegrin And Metalloprotease 12 (ADAM12); Human A Disintegrin And Metalloprotease 12 (ADAM12) ELISA Kit; MCMP; MCMPMltna; MLTN; MLTNA; Meltrin Alpha; Disintegrin and metalloproteinase domain-containing protein 12; ADAM12 elisa kit

• Reactivity: Human
• Sequence Length: 737

• Samples: Serum, plasma, tissue homogenates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 78.125-5000pg/mL
• Sensitivity: 28pg/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 572882491
• NCBI GeneID: 8038
• NCBI Accession #: NP_001275903.1
• NCBI GenBank Nucleotide #: NM_001288974.1
• UniProt Accession #: O43184; O60470; Q5JRP0; Q5JRP1; Q6P9E3; Q6UWB0
• Molecular Weight: 80,263 Da
• NCBI Official Full Name: disintegrin and metalloproteinase domain-containing protein 12 isoform 4 preproprotein
• NCBI Official Synonym Full Names: ADAM metallopeptidase domain 12
• NCBI Official Symbol: ADAM12
• NCBI Official Synonym Symbols: MCMP; MLTN; CAR10; MLTNA; MCMPMltna; ADAM12-OT1
• NCBI Protein Information: disintegrin and metalloproteinase domain-containing protein 12
• UniProt Protein Name: Disintegrin and metalloproteinase domain-containing protein 12
• Protein Family: Disintegrin and metalloproteinase domain-containing protein
• UniProt Gene Name: ADAM12
• UniProt Synonym Gene Names: MLTN; ADAM 12

NCBI Description

This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form. [provided by RefSeq, Jan 2014]

Uniprot Description

Involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Also involved in macrophage-derived giant cells (MGC) and osteoclast formation from mononuclear precursors ().