Western Blot (WB)
(Anti-INDOL1 antibody, MBS175296, Western blottingLane 1: A549 Cell LysateLane 2: Human Placenta Tissue LysateLane 3: A431 Cell Lysate )
Rabbit anti-Human INDOL1 Polyclonal Antibody | anti-IDO2 antibody
Anti-INDOL1 antibody
Gene Names
IDO2; INDOL1
Reactivity
Human
Applications
Western Blot
Purity
Immunogen affinity purified.
Synonyms
INDOL1; Polyclonal Antibody; Anti-INDOL1 antibody; ndoleamine 2; 3-dioxygenase 2; indoleamine 2; 3-dioxygenase 2 antibody; 3-dioxygenase-like protein 1 antibody; EC 1.13.11. antibody; I23O2_HUMAN antibody; IDO 2 antibody; IDO-2 antibody; Ido2 antibody; INDOL 1 antibody; Indoleamine 2 antibody; Indoleamine 2; 3 dioxygenase 2 antibody; 3 dioxygenase like 1 protein antibody; 3 dioxygenase like protein 1 antibody; Indoleamine pyrrole 2; 3 dioxygenase like 1 antibody; Indoleamine-pyrrole 2 antibody; anti-IDO2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
407
Applicable Applications for anti-IDO2 antibody
Western Blot (WB)
Application Notes
WB: Concentration: 0.1-0.5ug/ml; Tested Species: Human
FC: Concentration: 1-3ug/1x106; Tested Species: Human
Tested Species: In house treated species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarites.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Antibody can be supported by Chemiluminescent Kit MBS176460 in Western Blot.
FC: Concentration: 1-3ug/1x106; Tested Species: Human
Tested Species: In house treated species with positive results.
Predicted Species: Species predicted to be fit for the product based on sequence similarites.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
Antibody can be supported by Chemiluminescent Kit MBS176460 in Western Blot.
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human INDOL1 (1-20aa MLHFHYYDTSNKIMEPHRPN).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Western Blot (WB)
(Anti-INDOL1 antibody, MBS175296, Western blottingLane 1: A549 Cell LysateLane 2: Human Placenta Tissue LysateLane 3: A431 Cell Lysate )
Western Blot (WB)
(Anti-INDOL1 antibody, MBS175296, Western blottingLane 1: A549 Cell LysateLane 2: Human Placenta Tissue LysateLane 3: A431 Cell Lysate )
Related Product Information for anti-IDO2 antibody
IDO2(Indoleamine 2,3-dioxygenase 2), also called INDOLEAMINE 2,3-DIOXYGENASE-LIKE 1 or INDOL1, is an enzyme encoded by theINDOL1 gene which metabolizes tryptophan in the kynurenine pathway. By genomic sequence analysis, the INDOL1 gene is mapped onchromosome 8p12 just downstream of the INDO gene. And its exact cytogenetic location is 8p11.21. By database analysis using INDO asprobe, followed by RT-PCR of total RNA from various tissues, IDO2 is cloned by human and mouse INDOL1. INDOL1 catabolizes tryptophan asdetermined by Kyn production, but unlike INDO, is inhibited by D-1-methyl-tryptophan(D-1MT) but not the L-1MT stereoisomer. The GeneStructure of the INDOL1 has 11 exons and spans 74 kb.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Indoleamine 2,3-dioxygenase 2
NCBI Official Synonym Full Names
indoleamine 2,3-dioxygenase 2
NCBI Official Symbol
IDO2
NCBI Official Synonym Symbols
INDOL1
NCBI Protein Information
indoleamine 2,3-dioxygenase 2; IDO-2; indoleamine 2,3-dioxygenase-like 1 protein; indoleamine 2,3-dioxygenase-like protein 1; indoleamine-pyrrole 2,3 dioxygenase-like 1; indoleamine-pyrrole 2,3-dioxygenase-like protein 1
UniProt Protein Name
Indoleamine 2,3-dioxygenase 2
Protein Family
UniProt Gene Name
IDO2
UniProt Synonym Gene Names
INDOL1; IDO-2
UniProt Entry Name
I23O2_HUMAN
NCBI Description
Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007 [PubMed 17499941]).[supplied by OMIM, Feb 2011]
Uniprot Description
INDOL1: Catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan catabolism. Belongs to the indoleamine 2,3-dioxygenase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - tryptophan; Oxidoreductase; EC 1.13.11.-
Chromosomal Location of Human Ortholog: 8p11.21
Cellular Component: cytoplasm; cytosol
Molecular Function: metal ion binding; heme binding; indoleamine 2,3-dioxygenase activity; tryptophan 2,3-dioxygenase activity
Biological Process: tryptophan catabolic process to kynurenine; tryptophan catabolic process
Research Articles on IDO2
Similar Products
Product Notes
The IDO2 ido2 (Catalog #AAA175296) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-INDOL1 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's INDOL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: Concentration: 0.1-0.5ug/ml; Tested Species: Human FC: Concentration: 1-3ug/1x106; Tested Species: Human Tested Species: In house treated species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarites. Other applications have not been tested. Optimal dilutions should be determined by end users. Antibody can be supported by Chemiluminescent Kit MBS176460 in Western Blot. Researchers should empirically determine the suitability of the IDO2 ido2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "INDOL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
