Western Blot (WB)
(Western blot analysis of Human fetal brain tissue and Human kidney tissue using IDO2 Polyclonal Antibody at dilution of 1:450)
Rabbit anti-Human IDO2 Polyclonal Antibody | anti-IDO2 antibody
IDO2 Polyclonal Antibody
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
IDO2; Polyclonal Antibody; IDO2 Polyclonal Antibody; 3-dioxygenase 2; 3-dioxygenase-like protein 1; EC 1.13.11.; I23O2; IDO 2; IDO-2; Ido2; INDOL 1; Indoleamine 2; 3 dioxygenase 2; 3 dioxygenase like 1 protein; 3 dioxygenase like protein 1; Indoleamine pyrrole 2; 3 dioxygenase like 1; Indoleamine-pyrrole 2; anti-IDO2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
1mg/mL (varies by lot)
Sequence Length
407
Applicable Applications for anti-IDO2 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
IHC: 1:30-1:150
ELISA: 1:5000-1:10000
IHC: 1:30-1:150
ELISA: 1:5000-1:10000
Immunogen
Full length fusion protein
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of Human fetal brain tissue and Human kidney tissue using IDO2 Polyclonal Antibody at dilution of 1:450)
Western Blot (WB)
(Western blot analysis of Human fetal brain tissue and Human kidney tissue using IDO2 Polyclonal Antibody at dilution of 1:450)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human brain tissue using IDO2 Polyclonal Antibody at dilution of 1:45(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human brain tissue using IDO2 Polyclonal Antibody at dilution of 1:45(×200))
Related Product Information for anti-IDO2 antibody
INDOL1 is also known as IDO2 (indoleamine 2, 3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2, 3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, two single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.
Product Categories/Family for anti-IDO2 antibody
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
45 kDa
NCBI Official Full Name
Indoleamine 2,3-dioxygenase 2
UniProt Protein Name
Indoleamine 2,3-dioxygenase 2
Protein Family
UniProt Gene Name
IDO2
UniProt Synonym Gene Names
INDOL1; IDO-2
UniProt Entry Name
I23O2_HUMAN
Uniprot Description
INDOL1: Catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan catabolism. Belongs to the indoleamine 2,3-dioxygenase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - tryptophan; Oxidoreductase; EC 1.13.11.-
Chromosomal Location of Human Ortholog: 8p11.21
Cellular Component: cytoplasm; cytosol
Molecular Function: metal ion binding; heme binding; indoleamine 2,3-dioxygenase activity; tryptophan 2,3-dioxygenase activity
Biological Process: tryptophan catabolic process to kynurenine; tryptophan catabolic process
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Product Notes
The IDO2 ido2 (Catalog #AAA2560264) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IDO2 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IDO2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500-1:2000 IHC: 1:30-1:150 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the IDO2 ido2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IDO2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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