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Immunohistochemistry (IHC) (Anti-INADL antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)

Goat INADL / PATJ Polyclonal Antibody | anti-INADL antibody

Goat Polyclonal to Human INADL / PATJ

Gene Names
INADL; Cipp; PATJ; hINADL; InaD-like
Reactivity
Gibbon, Bovine, Human, Monkey, Rabbit
Predicted Reactivity: Bat, Dog, Horse (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry, ELISA
Purity
Immunoaffinity Purified
Synonyms
INADL / PATJ; Polyclonal Antibody; Goat Polyclonal to Human INADL / PATJ; Anti-INADL / PATJ Antibody (N-Terminus) IHC-plus; INADL; Cipp; HINADL; InaD-like (Drosophila); InaD-like protein; InaD-like; Inadl protein; PATJ; Inadl; c-term variant3; PDZ domain protein; Human INADL; anti-INADL antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Gibbon, Bovine, Human, Monkey, Rabbit
Predicted Reactivity: Bat, Dog, Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human INADL.
Purity/Purification
Immunoaffinity Purified
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
1801
Applicable Applications for anti-INADL antibody
Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
Application Notes
ELISA (1:32000), IHC-P (3.75 ug/ml)
Target Species
Human
Immunogen Description
Synthetic peptide PENPATDKLQVLQ-C from the N-terminus of human INADL (NP_795352.2). Percent identity by BLAST analysis: Human, Gibbon, Marmoset, Bovine, Rabbit (100%); Panda, Dog, Bat, Horse (92%); Elephant, Turkey, Chicken (85%).
Immunogen Type
Synthetic peptide
Immunogen
INADL / PATJ antibody was raised against synthetic peptide PENPATDKLQVLQ-C from the N-terminus of human INADL (NP_795352.2). Percent identity by BLAST analysis: Human, Gibbon, Marmoset, Bovine, Rabbit (100%); Panda, Dog, Bat, Horse (92%); Elephant, Turkey, Chicken (85%).
Antigen Modification
N-Terminus
Preparation and Storage
Store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

(Anti-INADL antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)

Immunohistochemistry (IHC) (Anti-INADL antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
125,231 Da
NCBI Official Full Name
inaD-like protein
NCBI Official Synonym Full Names
InaD-like (Drosophila)
NCBI Official Symbol
INADL
NCBI Official Synonym Symbols
Cipp; PATJ; hINADL; InaD-like
NCBI Protein Information
inaD-like protein; PDZ domain protein; protein associated to tight junctions; channel-interacting PDZ domain protein; PALS1-associated tight junction protein; inactivation no after-potential D-like protein
UniProt Protein Name
InaD-like protein
UniProt Gene Name
INADL
UniProt Synonym Gene Names
PATJ; Inadl protein; hINADL
UniProt Entry Name
INADL_HUMAN

NCBI Description

This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors. [provided by RefSeq, Jul 2008]

Uniprot Description

INADL: Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 1p31.3

Cellular Component: tight junction; protein complex; perinuclear region of cytoplasm; apical plasma membrane; plasma membrane

Molecular Function: protein binding

Biological Process: intercellular junction assembly and maintenance

Research Articles on INADL

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Product Notes

The INADL inadl (Catalog #AAA247671) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat Polyclonal to Human INADL / PATJ reacts with Gibbon, Bovine, Human, Monkey, Rabbit Predicted Reactivity: Bat, Dog, Horse (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's INADL / PATJ can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), ELISA (EIA). ELISA (1:32000), IHC-P (3.75 ug/ml). Researchers should empirically determine the suitability of the INADL inadl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "INADL / PATJ, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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