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Western Blot (WB) (Mouse Plk2 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the Plk2 antibody detected the Plk2 protein (arrow).)

Rabbit Plk2 Polyclonal Antibody | anti-Plk2 antibody

Mouse Plk2 Antibody (Center)

Gene Names
Plk2; Snk
Reactivity
Human, mouse (Predicted Reactivity: Rat)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
Plk2; Polyclonal Antibody; Mouse Plk2 Antibody (Center); Serine/threonine-protein kinase PLK2; Polo-like kinase 2; PLK-2; Serine/threonine-protein kinase SNK; Serum-inducible kinase; Snk; anti-Plk2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, mouse (Predicted Reactivity: Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Mouse Plk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 354-382 amino acids from the Central region of mouse Plk2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
354-382
Sequence Length
682
Applicable Applications for anti-Plk2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
MOUSE
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Mouse Plk2 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the Plk2 antibody detected the Plk2 protein (arrow).)

Western Blot (WB) (Mouse Plk2 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the Plk2 antibody detected the Plk2 protein (arrow).)

Western Blot (WB)

(Mouse Plk2 Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Plk2 antibody detected the Plk2 protein (arrow).)

Western Blot (WB) (Mouse Plk2 Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Plk2 antibody detected the Plk2 protein (arrow).)
Related Product Information for anti-Plk2 antibody
Plk2 may play a role in the division of at least some cell types, such as fibroblasts, and could function in embryogenesis, wound healing or neoplasia.
Product Categories/Family for anti-Plk2 antibody
References
Hutchins, J.R., et al. Science 328(5978):593-599(2010)
Inglis, K.J., et al. J. Biol. Chem. 284(5):2598-2602(2009)
Park, Y.Y., et al. Biochem. Biophys. Res. Commun. 362(1):107-113(2007)
Nishimura, M., et al. DNA Res. 11(5):315-323(2004)
Ma, S., et al. Mol. Cell. Biol. 23(19):6936-6943(2003)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
77812
NCBI Official Full Name
serine/threonine-protein kinase PLK2
NCBI Official Synonym Full Names
polo-like kinase 2
NCBI Official Symbol
Plk2
NCBI Official Synonym Symbols
Snk
NCBI Protein Information
serine/threonine-protein kinase PLK2
UniProt Protein Name
Serine/threonine-protein kinase PLK2
UniProt Gene Name
Plk2
UniProt Synonym Gene Names
Snk; PLK-2
UniProt Entry Name
PLK2_MOUSE

Uniprot Description

PLK2: a kinase of the PLK family. Participates in a mitotic checkpoint in which p53-dependent activation Plk2 prevents mitotic catastrophe following spindle damage. Plk2(-/-) embryos show retarded growth and skeletal development late in gestation. Apparently plays a role for Plk2 in the cell cycle.

Protein type: Kinase, protein; Tumor suppressor; Protein kinase, Other; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.21; Other group; PLK family

Cellular Component: centriole; centrosome; cytoskeleton; cell projection; cytoplasm; dendrite; intracellular; chromatin

Molecular Function: transferase activity; protein serine/threonine kinase activity; signal transducer activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; protein complex binding; kinase activity; ATP binding; protein kinase activity

Biological Process: regulation of centriole replication; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of protein binding; mitotic cell cycle checkpoint; regulation of synaptic plasticity; protein amino acid phosphorylation; memory; mitotic spindle organization and biogenesis; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; Ras protein signal transduction; mitotic cell cycle; phosphorylation; Rap protein signal transduction; G1/S transition of mitotic cell cycle; negative regulation of apoptosis

Research Articles on Plk2

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Product Notes

The Plk2 plk2 (Catalog #AAA9208707) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 354-382. The Mouse Plk2 Antibody (Center) reacts with Human, mouse (Predicted Reactivity: Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's Plk2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Plk2 plk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Plk2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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