Western Blot (WB)
(Anti-IL5RA antibody, MBS175245, Western blottingAll lanes: Anti IL5RA (MBS175245) at 0.5ug/mlLane 1: A549 Whole Cell Lysate at 40ugLane 2: SMMC Whole Cell Lysate at 40ugLane 3: U87 Whole Cell Lysate at 40ugLane 4: 293T Whole Cell Lysate at 40ugLane 5: PANC Whole Cell Lysate at 40ugLane 6: HELA Whole Cell Lysate at 40ugLane 7: JURKAT Whole Cell Lysate at 40ugLane 8: RAJI Whole Cell Lysate at 40ugLane 9: CEM Whole Cell Lysate at 40ugPredicted bind size: 48KDObserved bind size: 60KD )
Rabbit anti-Human IL5RA Polyclonal Antibody | anti-IL5RA antibody
Anti-IL5RA antibody
Western Blot (WB)
(Anti-IL5RA antibody, MBS175245, Western blottingAll lanes: Anti IL5RA (MBS175245) at 0.5ug/mlLane 1: A549 Whole Cell Lysate at 40ugLane 2: SMMC Whole Cell Lysate at 40ugLane 3: U87 Whole Cell Lysate at 40ugLane 4: 293T Whole Cell Lysate at 40ugLane 5: PANC Whole Cell Lysate at 40ugLane 6: HELA Whole Cell Lysate at 40ugLane 7: JURKAT Whole Cell Lysate at 40ugLane 8: RAJI Whole Cell Lysate at 40ugLane 9: CEM Whole Cell Lysate at 40ugPredicted bind size: 48KDObserved bind size: 60KD )
Western Blot (WB)
(Anti-IL5RA antibody, MBS175245, Western blottingAll lanes: Anti IL5RA (MBS175245) at 0.5ug/mlLane 1: A549 Whole Cell Lysate at 40ugLane 2: SMMC Whole Cell Lysate at 40ugLane 3: U87 Whole Cell Lysate at 40ugLane 4: 293T Whole Cell Lysate at 40ugLane 5: PANC Whole Cell Lysate at 40ugLane 6: HELA Whole Cell Lysate at 40ugLane 7: JURKAT Whole Cell Lysate at 40ugLane 8: RAJI Whole Cell Lysate at 40ugLane 9: CEM Whole Cell Lysate at 40ugPredicted bind size: 48KDObserved bind size: 60KD )
Background: IL5RA(INTERLEUKIN 5 RECEPTOR, ALPHA), also known as CD125, is a subunit of the Interleukin-5 receptor. IL5RA also denotes its human gene. The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor which is composed of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2(CSF2/GM-CSF), and interleukin 5(IL5). The IL5RA gene is mapped to 3p26-p24 by Southern blot analysis of DNA from a panel of mouse-human hybrid somatic cell lines complemented by in situ hybridization. And its Cytogenetic location is 3p26.2. Within this 15-residue stretch of IL5RA, the C-terminal phenylalanine is critical. The binding of this protein to IL5 depends on the beta subunit which is activated by the ligand binding and is required for the biological activities of IL5.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011]
Uniprot Description
IL5RA: This is the receptor for interleukin-5. The alpha chain binds to IL5. Belongs to the type I cytokine receptor family. Type 5 subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Receptor, cytokine; Membrane protein, integral
Chromosomal Location of Human Ortholog: 3p26-p24
Cellular Component: extracellular space; plasma membrane; integral to membrane
Molecular Function: protein binding; interleukin-5 receptor activity
Biological Process: cell proliferation; regulation of interleukin-5 production; inflammatory response to antigenic stimulus; signal transduction
Research Articles on IL5RA
Similar Products
Product Notes
The IL5RA il5ra (Catalog #AAA175245) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-IL5RA antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL5RA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the IL5RA il5ra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL5RA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
