Testing Data
Rabbit anti-Human, Mouse IKB-epsilon Polyclonal Antibody | anti-IKB-epsilon antibody
Anti-IKB-epsilon Antibody
Gene Names
Nfkbie; IKBE; IkB-E; ikB-epsilon; NF-kappa-BIE; I-kappa-B-epsilon
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Synonyms
IKB-epsilon; Polyclonal Antibody; Anti-IKB-epsilon Antibody; anti-IKB-epsilon antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Clone Number
SAB
Specificity
IkB-epsilon (Ab-22) antibody detects endogenous levels of total IkB-epsilon protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Form/Format
Liquid
Concentration
1ug/ul (varies by lot)
Sequence Length
364
Applicable Applications for anti-IKB-epsilon antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:100
IHC: 1:50~1:100
Storage Buffer
phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human IkB-epsilon around the phosphorylation site of serine 22 (I-E-SP-L-R).
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Testing Data
Testing Data
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
39,200 Da
NCBI Official Full Name
IkB epsilon
NCBI Official Synonym Full Names
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
NCBI Official Symbol
Nfkbie
NCBI Official Synonym Symbols
IKBE; IkB-E; ikB-epsilon; NF-kappa-BIE; I-kappa-B-epsilon
NCBI Protein Information
NF-kappa-B inhibitor epsilon; ikappaBepsilon; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
UniProt Protein Name
NF-kappa-B inhibitor epsilon
UniProt Gene Name
Nfkbie
UniProt Entry Name
IKBE_MOUSE
Uniprot Description
IkB-epsilon: Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes. Interacts with RELA, REL, NFKB1 nuclear factor NF-kappa-B p50 subunit and NFKB2 nuclear factor NF-kappa-B p52 subunit. Highly expressed in spleen, testis and lung, followed by kidney, pancreas, heart, placenta and brain. Also expressed in granulocytes and macrophages. Belongs to the NF-kappa-B inhibitor family.
Protein type: DNA-binding; Inhibitor
Cellular Component: Golgi apparatus; perinuclear region of cytoplasm; cytoplasm
Molecular Function: protein binding
Biological Process: negative regulation of transcription, DNA-dependent; D-serine transport
Research Articles on IKB-epsilon
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Product Notes
The IKB-epsilon nfkbie (Catalog #AAA417290) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-IKB-epsilon Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IKB-epsilon can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500~1:1000 IHC: 1:50~1:100. Researchers should empirically determine the suitability of the IKB-epsilon nfkbie for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IKB-epsilon, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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