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Western Blot (WB) (Western blotAll lanes: IgG receptor FcRn large subunit p51 antibody at 2ug/mlLane 1:HepG2 whole cell lysateLane 2:mouse liver tissueLane 3:mouse spleen tissueLane 4:A549 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 40kDaObserved band size: 40kDa)

Rabbit IgG receptor FcRn large subunit p51 Polyclonal Antibody | anti-IgG antibody

Rabbit anti-human IgG receptor FcRn large subunit p51 polyclonal Antibody

Gene Names
FCGRT; FCRN; alpha-chain
Reactivity
Human, Mouse. Other species are not tested. Please decide the specificity by homology
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Caprylic Acid Ammonium Sulfate Precipitation Purified
Synonyms
IgG receptor FcRn large subunit p51; Polyclonal Antibody; Rabbit anti-human IgG receptor FcRn large subunit p51 polyclonal Antibody; IgG Fc fragment receptor transporter alpha chain FCGRT FCRN; anti-IgG antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse. Other species are not tested. Please decide the specificity by homology
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Sequence Length
365
Applicable Applications for anti-IgG antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human IgG receptor FcRn large subunit p51 protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-46328 / sc-46326 / sc-46330 / sc-46329 / sc-66893 / sc-66892
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: IgG receptor FcRn large subunit p51 antibody at 2ug/mlLane 1:HepG2 whole cell lysateLane 2:mouse liver tissueLane 3:mouse spleen tissueLane 4:A549 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 40kDaObserved band size: 40kDa)

Western Blot (WB) (Western blotAll lanes: IgG receptor FcRn large subunit p51 antibody at 2ug/mlLane 1:HepG2 whole cell lysateLane 2:mouse liver tissueLane 3:mouse spleen tissueLane 4:A549 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 40kDaObserved band size: 40kDa)

Western Blot (WB)

(Western blotAll lanes: FCGRT antibody at 5.3 ug/mlLane 1: Mouse liver tissueLane 2: Mouse kidney tissueSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 39 kDaObserved band size: 39 kDa)

Western Blot (WB) (Western blotAll lanes: FCGRT antibody at 5.3 ug/mlLane 1: Mouse liver tissueLane 2: Mouse kidney tissueSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 39 kDaObserved band size: 39 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human placenta tissue using MBS1488262 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human placenta tissue using MBS1488262 at dilution 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human Pancreatic Cancer using MBS1488262 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human Pancreatic Cancer using MBS1488262 at dilution 1:100)

Immunofluorescence (IF)

(Immunofluorescent analysis of HepG2 cells using MBS1488262 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

Immunofluorescence (IF) (Immunofluorescent analysis of HepG2 cells using MBS1488262 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39,743 Da
NCBI Official Full Name
IgG receptor FcRn large subunit p51
NCBI Official Synonym Full Names
Fc fragment of IgG receptor and transporter
NCBI Official Symbol
FCGRT
NCBI Official Synonym Symbols
FCRN; alpha-chain
NCBI Protein Information
IgG receptor FcRn large subunit p51
UniProt Protein Name
IgG receptor FcRn large subunit p51
Protein Family
UniProt Gene Name
FCGRT
UniProt Synonym Gene Names
FCRN; FcRn
UniProt Entry Name
FCGRN_HUMAN

NCBI Description

This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

Uniprot Description

FCGRT: Binds to the Fc region of monomeric immunoglobulins gamma. Mediates the uptake of IgG from milk. Possible role in transfer of immunoglobulin G from mother to fetus. Belongs to the immunoglobulin superfamily.

Protein type: Membrane protein, integral; Immunoglobulin superfamily; Receptor, misc.

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: integral to membrane; plasma membrane

Molecular Function: antigen binding; beta-2-microglobulin binding; IgG binding; IgG receptor activity; peptide antigen binding

Biological Process: antigen processing and presentation; IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor; immune response

Research Articles on IgG

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Product Notes

The IgG fcgrt (Catalog #AAA1488262) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human IgG receptor FcRn large subunit p51 polyclonal Antibody reacts with Human, Mouse. Other species are not tested. Please decide the specificity by homology and may cross-react with other species as described in the data sheet. AAA Biotech's IgG receptor FcRn large subunit p51 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the IgG fcgrt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IgG receptor FcRn large subunit p51, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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