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Western Blot (WB) (Western blot analysis of extracts from NIH-3T3 cells, using ICAM2 antibody.)

Rabbit anti-Human, Mouse ICAM2 Polyclonal Antibody | anti-ICAM2 antibody

ICAM2 Antibody

Gene Names
ICAM2; CD102
Reactivity
Human, Mouse
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
ICAM2; Polyclonal Antibody; ICAM2 Antibody; Intercellular adhesion molecule 2; ICAM-2; CD102 antigen; CD102; anti-ICAM2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total ICAM2 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
275
Applicable Applications for anti-ICAM2 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500~1:3000
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from internal of human ICAM2.
Target Name
ICAM2
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from NIH-3T3 cells, using ICAM2 antibody.)

Western Blot (WB) (Western blot analysis of extracts from NIH-3T3 cells, using ICAM2 antibody.)
Related Product Information for anti-ICAM2 antibody
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.Staunton D.E., Nature 339:61-64(1989).Garcia-Aguilar J., Submitted (FEB-1990) to the EMBL/GenBank/DDBJ databases.Xu G., Proc. Natl. Acad. Sci. U.S.A. 106:19310-19315(2009).
Product Categories/Family for anti-ICAM2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
30,654 Da
NCBI Official Full Name
intercellular adhesion molecule 2
NCBI Official Synonym Full Names
intercellular adhesion molecule 2
NCBI Official Symbol
ICAM2
NCBI Official Synonym Symbols
CD102
NCBI Protein Information
intercellular adhesion molecule 2
UniProt Protein Name
Intercellular adhesion molecule 2
UniProt Gene Name
ICAM2
UniProt Synonym Gene Names
ICAM-2
UniProt Entry Name
ICAM2_HUMAN

NCBI Description

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

ICAM2: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen- specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Belongs to the immunoglobulin superfamily. ICAM family.

Protein type: Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 17q23.3

Cellular Component: membrane; integral to plasma membrane; plasma membrane; uropod

Molecular Function: integrin binding

Biological Process: extracellular matrix organization and biogenesis; cell-cell adhesion; regulation of immune response; cell adhesion

Research Articles on ICAM2

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Product Notes

The ICAM2 icam2 (Catalog #AAA9402503) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ICAM2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ICAM2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500~1:3000. Researchers should empirically determine the suitability of the ICAM2 icam2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ICAM2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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