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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human pancreatic cancer using MBS1495764 at dilution of 1:100)

Rabbit anti-Human DPY30 Polyclonal Antibody | anti-DPY30 antibody

DPY30 Antibody

Gene Names
DPY30; Cps25; Saf19; HDPY-30
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
>95%, Protein G Purified
Synonyms
DPY30; Polyclonal Antibody; DPY30 Antibody; Protein dpy-30 homolog; Dpy-30-like protein; Dpy-30L; anti-DPY30 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G Purified
Sequence Length
99
Applicable Applications for anti-DPY30 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Protein dpy-30 homolog protein
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-167677
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human pancreatic cancer using MBS1495764 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human pancreatic cancer using MBS1495764 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS1495764 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS1495764 at dilution of 1:100)
Related Product Information for anti-DPY30 antibody
As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
11,250 Da
NCBI Official Full Name
protein dpy-30 homolog
NCBI Official Synonym Full Names
dpy-30, histone methyltransferase complex regulatory subunit
NCBI Official Symbol
DPY30
NCBI Official Synonym Symbols
Cps25; Saf19; HDPY-30
NCBI Protein Information
protein dpy-30 homolog
UniProt Protein Name
Protein dpy-30 homolog
UniProt Gene Name
DPY30
UniProt Synonym Gene Names
Dpy-30L
UniProt Entry Name
DPY30_HUMAN

NCBI Description

DPY30 is a component of a Set1-like multiprotein histone methyltransferase complex (Cho et al., 2007 [PubMed 17500065]).[supplied by OMIM, May 2008]

Uniprot Description

DPY30: As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. Belongs to the dpy-30 family.

Chromosomal Location of Human Ortholog: 2p22.3

Cellular Component: chromosome, telomeric region; Golgi apparatus; histone methyltransferase complex; nucleoplasm; nucleus; trans-Golgi network

Molecular Function: histone lysine N-methyltransferase activity (H3-K4 specific); identical protein binding; protein binding; protein homodimerization activity

Biological Process: chromatin silencing at telomere; endosome transport; establishment and/or maintenance of chromatin architecture; histone H3-K4 methylation; transcription, DNA-dependent

Research Articles on DPY30

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Product Notes

The DPY30 dpy30 (Catalog #AAA1495764) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DPY30 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DPY30 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the DPY30 dpy30 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DPY30, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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