Western Blot (WB)
(Western Blot: Sample: Lane1: Porcine Kidney Tissue; Lane2: Human HeLa Cells; Lane3: Porcine Brain Tissue.)
Rabbit anti-Human Huntingtin Interacting Protein 12 Polyclonal Antibody | anti-HIP12 antibody
Polyclonal Antibody to Huntingtin Interacting Protein 12 (HIP12)
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Lane1: Porcine Kidney Tissue; Lane2: Human HeLa Cells; Lane3: Porcine Brain Tissue.)
Western Blot (WB)
(Western Blot: Sample: Lane1: Porcine Kidney Tissue; Lane2: Human HeLa Cells; Lane3: Porcine Brain Tissue.)
Western Blot (WB)
(Western Blot: Sample: Recombinant HIP12, Human.)
Western Blot (WB)
(Western Blot: Sample: Recombinant HIP12, Human.)
Immunohistochemistry (IHC)
(FITC staining on IHC-P; Samples: Human Hela Cells.)
Immunohistochemistry (IHC)
(FITC staining on IHC-P; Samples: Human Hela Cells.)
NCBI and Uniprot Product Information
Uniprot Description
HIP1R: Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3- phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. Belongs to the SLA2 family.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 12q24.31
Cellular Component: apical plasma membrane; cell cortex; cell soma; clathrin-coated pit; clathrin-coated vesicle; clathrin-coated vesicle membrane; cytoskeleton; cytosol; dendrite cytoplasm; dendritic spine; intracellular membrane-bound organelle; mitochondrion; perinuclear region of cytoplasm; postsynaptic density
Molecular Function: actin filament binding; clathrin binding; clathrin light chain binding; phosphatidylinositol binding; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-4,5-bisphosphate binding; protein binding; protein heterodimerization activity; protein homodimerization activity; SH3 domain binding
Biological Process: activation of cysteine-type endopeptidase activity involved in apoptotic process; apoptosis; clathrin coat assembly; negative regulation of actin filament polymerization; negative regulation of apoptosis; positive regulation of apoptosis; positive regulation of epidermal growth factor receptor signaling pathway; positive regulation of protein binding; protein stabilization; receptor-mediated endocytosis; regulation of actin cytoskeleton organization; regulation of endocytosis
Research Articles on HIP12
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Product Notes
The HIP12 hip1r (Catalog #AAA2027172) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Huntingtin Interacting Protein 12 (HIP12) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Huntingtin Interacting Protein 12 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.5-2ug/ml Immunocytochemistry in formalin fixed cells: 5-20ug/ml Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml Immunohistochemistry in paraffin section: 5-20ug/ml Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml Optimal working dilutions must be determined by end user. Researchers should empirically determine the suitability of the HIP12 hip1r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Huntingtin Interacting Protein 12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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