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Rabbit HMG17 Polyclonal Antibody | anti-HMG17 antibody

HMG17 (Phospho-Ser29) Antibody

Gene Names
HMGN2; HMG17
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, ELISA
Purity
Purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Synonyms
HMG17; Polyclonal Antibody; HMG17 (Phospho-Ser29) Antibody; high mobility group protein N2; high-mobility group (nonhistone chromosomal) protein 17; high-mobility group nucleosomal binding domain 2; high-mobility group nucleosome binding domain 2; nonhistone chromosomal protein HMG-17; anti-HMG17 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
HMG17 (Phospho-Ser29) Antibody detects endogenous levels of HMG17 only when phosphorylated at Ser29.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (varies by lot)
Sequence Length
90
Applicable Applications for anti-HMG17 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50~1:100
ELISA: 1:10000
Target Modification
Phospho
Modification Sites
H:S29; M:S29; R:S29
Immunogen
The antiserum was produced against synthesized peptide derived from human HMG17 around the phosphorylation site of Ser29.
Immunogen Range
Jan-50
Preparation and Storage
Stable at -20 degree C for at least 1 year.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
9 kDa
NCBI Official Full Name
non-histone chromosomal protein HMG-17
NCBI Official Synonym Full Names
high mobility group nucleosomal binding domain 2
NCBI Official Symbol
HMGN2
NCBI Official Synonym Symbols
HMG17
NCBI Protein Information
non-histone chromosomal protein HMG-17
UniProt Protein Name
Non-histone chromosomal protein HMG-17
UniProt Gene Name
HMGN2
UniProt Synonym Gene Names
HMG17

NCBI Description

The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi. [provided by RefSeq, Oct 2014]

Uniprot Description

Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation ().

Research Articles on HMG17

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Product Notes

The HMG17 hmgn2 (Catalog #AAA9502822) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HMG17 (Phospho-Ser29) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HMG17 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50~1:100 ELISA: 1:10000. Researchers should empirically determine the suitability of the HMG17 hmgn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HMG17, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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