Rabbit HLTF Polyclonal Antibody | anti-HLTF antibody

HLTF Polyclonal Antibody

Cat. Num. AAA2517407

• Gene Names: HLTF; ZBU1; HLTF1; RNF80; HIP116; SNF2L3; HIP116A; SMARCA3
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Immunohistochemistry
• Purity: Antigen affinity purification
• Synonyms: HLTF; Polyclonal Antibody; HLTF Polyclonal Antibody; ZBU1; HLTF1; RNF80; HIP116; SNF2L3; HIP116A; SMARCA3; anti-HLTF antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen affinity purification
• Concentration: 1.6mg/mL (varies by lot)
• Sequence Length: 1009

• Applicable Applications for anti-HLTF antibody: ELISA (EIA), Immunohistochemistry (IHC)
• Application Notes: IHC: 1:50-1:100
• Immunogen: Synthetic peptide of human HLTF
• Buffer: PBS with 0.05% sodium azide, 50% glycerol, pH7.3
• Preparation and Storage: Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using HLTF Polyclonal Antibody at dilution 1:30)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using HLTF Polyclonal Antibody at dilution 1:30)

Related Product Information for anti-HLTF antibody

This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein.

Product Categories/Family for anti-HLTF antibody

Cell biology; Epigenetics

NCBI and Uniprot Product Information

• NCBI GI #: 21071054
• NCBI GeneID: 6596
• NCBI Accession #: NP_620636.1
• NCBI GenBank Nucleotide #: NM_139048.2
• Molecular Weight: 99,919 Da
• NCBI Official Full Name: helicase-like transcription factor
• NCBI Official Synonym Full Names: helicase-like transcription factor
• NCBI Official Symbol: HLTF
• NCBI Official Synonym Symbols: ZBU1; HLTF1; RNF80; HIP116; SNF2L3; HIP116A; SMARCA3
• NCBI Protein Information: helicase-like transcription factor; DNA-binding protein/plasminogen activator inhibitor 1 regulator; DNA-binding protein/plasminogen activator inhibitor-1 regulator; RING finger protein 80; SNF2-like 3; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3; sucrose nonfermenting protein 2-like 3; sucrose nonfermenting-like 3
• UniProt Protein Name: Helicase-like transcription factor
• Protein Family: Helicase-like transcription factor
• UniProt Gene Name: HLTF
• UniProt Synonym Gene Names: HIP116A; RNF80; SMARCA3; SNF2L3; ZBU1
• UniProt Entry Name: HLTF_HUMAN

NCBI Description

This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein. [provided by RefSeq, Jul 2008]

Uniprot Description

SMARCA3: an enzyme with apparent ATP-dependent DNA helicase activity. Belongs to the SNF2/RAD54 helicase family, RAD16 subfamily. Two alternatively spliced human isoforms have been described.

Protein type: Nucleolus; Ubiquitin conjugating system; Helicase; EC 3.6.4.-; DNA-binding; Ubiquitin ligase; EC 6.3.2.19; EC 3.6.1.-; EC 6.3.2.-; Ligase

Chromosomal Location of Human Ortholog: 3q25.1-q26.1

Cellular Component: nucleoplasm; membrane; cytoplasm; nucleolus; nucleus

Molecular Function: protein binding; DNA binding; zinc ion binding; ATPase activity; helicase activity; ATP binding; ligase activity

Biological Process: regulation of transcription from RNA polymerase II promoter; protein polyubiquitination; transcription, DNA-dependent; regulation of transcription, DNA-dependent; postreplication repair; chromatin modification