Rabbit anti-Human HGF activator (HGFA) Polyclonal Antibody | anti-HGF activator antibody
Rabbit anti Human HGF activator (HGFA) Polyclonal
Reactivity
Human
Applications
ELISA
Purity
Serum IgG fraction was purified by Protein A affinity chromatography.
Synonyms
HGF activator (HGFA); Polyclonal Antibody; Rabbit anti Human HGF activator (HGFA) Polyclonal; Rabbit anti Human HGF activator (HGFA) Polyclonal purified; HGF activator; HGFApolyclonal; PAb; anti-HGF activator antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Serum IgG fraction was purified by Protein A affinity chromatography.
Form/Format
0.2 um filtered solution in PBS with 5% trehalose.
Sequence Length
655
Applicable Applications for anti-HGF activator antibody
ELISA (EIA)
Application Notes
ELISA: Use at a concentration range of 0.5-1ug/ml. The detection limit for HGFA is approximately 0.16 ng/well.
Source Note
Polyclonal HGF activator antibody was produced from sera of rabbits immunized with recombinant human HGF activator.
Reconstitution
A quick spin of the vial followed by reconstitution in distilled water. This solution can then be diluted into other buffers.
Preparation and Storage
The lyophilized antibody is stable for at least 1 year from date of receipt at -20 degree C.
Upon reconstitution, this antibody can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C for six months without detectable loss of activity.
Avoid repeated freeze/thaw cycles.
Shelf Life: >12 months
Upon reconstitution, this antibody can be stored in working aliquots at 2 degree - 8 degree C for one month, or at -20 degree C for six months without detectable loss of activity.
Avoid repeated freeze/thaw cycles.
Shelf Life: >12 months
Related Product Information for anti-HGF activator antibody
HGF is a member of the plasminogen family of serine proteases although it lacks proteolytic activity. Like other members of this group, it is secreted as an inactive zymogen that must be activated by proteolytic cleavage.A specific serine protease, HGF activator (HGFA) has been shown to mediate activation of HGF. HGFA is expressed in adult liver and is secreted into the blood. Like other serine proteases in the coagulation and fibrinolytic cascades, HGF activator is secreted as an inactive single chain zymogen. It is cleaved to the catalytically active, disulfide-linked heterodimer by thrombin.
Product Categories/Family for anti-HGF activator antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
70,682 Da
NCBI Official Full Name
hepatocyte growth factor activator preproprotein
UniProt Protein Name
Hepatocyte growth factor activator
UniProt Gene Name
HGFAC
UniProt Synonym Gene Names
HGF activator; HGFA
UniProt Entry Name
HGFA_HUMAN
NCBI Description
This gene encodes a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Uniprot Description
HGFAC: Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form. Belongs to the peptidase S1 family.
Protein type: Secreted; Protease; Secreted, signal peptide; EC 3.4.21.-
Chromosomal Location of Human Ortholog: 4p16
Cellular Component: extracellular space; extracellular region
Molecular Function: serine-type peptidase activity; serine-type endopeptidase activity
Biological Process: proteolysis
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Product Notes
The HGF activator hgfac (Catalog #AAA551002) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Human HGF activator (HGFA) Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HGF activator (HGFA) can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: Use at a concentration range of 0.5-1ug/ml. The detection limit for HGFA is approximately 0.16 ng/well. Researchers should empirically determine the suitability of the HGF activator hgfac for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HGF activator (HGFA), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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