Western Blot (WB)
(Western blot analysis of HES2 using LOVO whole cell lysates)
Rabbit HES2 Polyclonal Antibody | anti-HES2 antibody
HES2 Antibody
Gene Names
HES2; bHLHb40
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
HES2; Polyclonal Antibody; HES2 Antibody; bHLHb40; Class B basic helix loop helix protein 40; Class B basic helix-loop-helix protein 40; Hairy and enhancer of split 2 (Drosophila); Hairy and enhancer of split 2; Hes2; HES2_HUMAN; Transcription factor HES 2; Transcription factor HES-2; anti-HES2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
HES2 antibody detects endogenous levels of total HES2
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
173
Applicable Applications for anti-HES2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:1000-3000
Immunogen
A synthesized peptide derived from human HES2
Subcellular Location
Nucleus.
Tissue Specificity
Expressed in placenta, pancreatic cancer, colon cancer with RER, cervical cancer, and in head and neck tumors.
Predicted Cross Reactivity
Rabbit
Similarity
Rabbit (83%)
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of HES2 using LOVO whole cell lysates)
Western Blot (WB)
(Western blot analysis of HES2 using LOVO whole cell lysates)
Related Product Information for anti-HES2 antibody
Function: Transcriptional repressor of genes that require a bHLH protein for their transcription.
Subunit Structure: Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family.
Similarity: Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG).The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins.
Subunit Structure: Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family.
Similarity: Has a particular type of basic domain (presence of a helix-interrupting proline) that binds to the N-box (CACNAG), rather than the canonical E-box (CANNTG).The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy-related proteins.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 18 kDa
Predicted: 19 kDa
Predicted: 19 kDa
NCBI Official Full Name
transcription factor HES-2
NCBI Official Synonym Full Names
hes family bHLH transcription factor 2
NCBI Official Symbol
HES2
NCBI Official Synonym Symbols
bHLHb40
NCBI Protein Information
transcription factor HES-2
UniProt Protein Name
Transcription factor HES-2
Protein Family
UniProt Gene Name
HES2
UniProt Synonym Gene Names
BHLHB40; bHLHb40
Uniprot Description
Transcriptional repressor of genes that require a bHLH protein for their transcription.
Similar Products
Product Notes
The HES2 hes2 (Catalog #AAA9608872) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HES2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HES2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:1000-3000. Researchers should empirically determine the suitability of the HES2 hes2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HES2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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