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Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human lung cancer using HDAC2 Polyclonal Antibody at dilution of 1:1000.)

Rabbit HDAC2 Polyclonal Antibody | anti-HDAC2 antibody

HDAC2 Polyclonal Antibody

Gene Names
Hdac2; YAF1; Yy1bp; mRPD3; D10Wsu179e
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry
Purity
Affinity Purification
Synonyms
HDAC2; Polyclonal Antibody; HDAC2 Polyclonal Antibody; D10Wsu179e; HD 2; HD2; HDAC 2; Hdac2; Histone deacetylase 2 (HD2); Histone deacetylase 2; OTTHUMP00000017046; OTTHUMP00000227077; OTTHUMP00000227078; RPD3; transcriptional regulator homolog RPD3; YAF1; YY1 associated factor 1; YY1 transcription factor binding protein; Yy1bp; anti-HDAC2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 100 mug/ml BSA and 50% glycerol.
Concentration
1.8 mg/mL (varies by lot)
Sequence Length
488
Applicable Applications for anti-HDAC2 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:500-1:2000
Immunogen
KLH conjugated synthetic peptide corresponding to Mouse HDAC2
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human lung cancer using HDAC2 Polyclonal Antibody at dilution of 1:1000.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human lung cancer using HDAC2 Polyclonal Antibody at dilution of 1:1000.)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded mouse liver using HDAC2 Polyclonal Antibody at dilution of 1:1000.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded mouse liver using HDAC2 Polyclonal Antibody at dilution of 1:1000.)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded Rat kidney using HDAC2 Polyclonal Antibody at dilution of 1:1000.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded Rat kidney using HDAC2 Polyclonal Antibody at dilution of 1:1000.)
Related Product Information for anti-HDAC2 antibody
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
Product Categories/Family for anti-HDAC2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
55,302 Da
NCBI Official Full Name
histone deacetylase 2
NCBI Official Synonym Full Names
histone deacetylase 2
NCBI Official Symbol
Hdac2
NCBI Official Synonym Symbols
YAF1; Yy1bp; mRPD3; D10Wsu179e
NCBI Protein Information
histone deacetylase 2
UniProt Protein Name
Histone deacetylase 2
UniProt Gene Name
Hdac2
UniProt Synonym Gene Names
Yy1bp; HD2

Uniprot Description

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (). Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. May be involved in the transcriptional repression of circadian target genes, such as PER1, mediated by CRY1 through histone deacetylation. Involved in MTA1-mediated transcriptional corepression of TFF1 and CDKN1A.

Research Articles on HDAC2

Similar Products

Product Notes

The HDAC2 hdac2 (Catalog #AAA2556261) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HDAC2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HDAC2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:500-1:2000. Researchers should empirically determine the suitability of the HDAC2 hdac2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HDAC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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