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Western Blot (WB) (WB Suggested Anti-HCN3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: COLO205 cell lysate)

Rabbit HCN3 Polyclonal Antibody | anti-HCN3 antibody

HCN3 antibody - middle region

Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Applications
Western Blot
Purity
Affinity Purified
Synonyms
HCN3; Polyclonal Antibody; HCN3 antibody - middle region; anti-HCN3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence
Synthetic peptide located within the following region: LQAAAVTSNVAIALTHQRGPLPLSPDSPATLLARSAWRSAGSPASPLVPV
Sequence Length
774
Applicable Applications for anti-HCN3 antibody
Western Blot (WB)
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 92%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 93%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human HCN3
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(WB Suggested Anti-HCN3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: COLO205 cell lysate)

Western Blot (WB) (WB Suggested Anti-HCN3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: COLO205 cell lysate)
Related Product Information for anti-HCN3 antibody
This is a rabbit polyclonal antibody against HCN3. It was validated on Western Blot using a cell lysate as a positive control.

Target Description: HCN3 is a putative hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions.
Product Categories/Family for anti-HCN3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
86kDa
NCBI Official Full Name
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
NCBI Official Synonym Full Names
hyperpolarization activated cyclic nucleotide gated potassium channel 3
NCBI Official Symbol
HCN3
NCBI Protein Information
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
UniProt Protein Name
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
UniProt Gene Name
HCN3
UniProt Synonym Gene Names
KIAA1535

NCBI Description

This gene encodes a multi-pass membrane protein that functions as a voltage gated cation channel. The encoded protein is a member of a family of closely related cyclic adenosine monophosphate-binding channel proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Uniprot Description

HCN3: Putative hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Belongs to the potassium channel HCN family.

Protein type: Channel, cation; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1q22

Cellular Component: axon; cell soma; cone cell pedicle; dendrite; integral component of plasma membrane; plasma membrane

Molecular Function: cAMP binding; protein binding; voltage-gated potassium channel activity; voltage-gated sodium channel activity

Biological Process: cellular response to cAMP; potassium ion transmembrane transport; regulation of ion transmembrane transport; regulation of membrane potential

Research Articles on HCN3

Similar Products

Product Notes

The HCN3 hcn3 (Catalog #AAA3202523) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HCN3 antibody - middle region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HCN3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the HCN3 hcn3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: LQAAAVTSNV AIALTHQRGP LPLSPDSPAT LLARSAWRSA GSPASPLVPV. It is sometimes possible for the material contained within the vial of "HCN3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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