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Western Blot (WB) (GTF2H2C Antibody(C-term) western blot analysis in A549,K562,MCF-7 cell line lysates (35ug/lane).This demonstrates the GTF2H2C antibody detected the GTF2H2C protein (arrow).)

Rabbit anti-Human GTF2H2C Polyclonal Antibody | anti-GTF2H2C antibody

GTF2H2C Antibody (C-term)

Gene Names
GTF2H2C_2; GTF2H2D
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Immunofluorescence, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
GTF2H2C; Polyclonal Antibody; GTF2H2C Antibody (C-term); General transcription factor IIH subunit 2-like protein; General transcription factor IIH polypeptide 2-like protein; anti-GTF2H2C antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This GTF2H2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-343 amino acids from the C-terminal region of human GTF2H2C.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.41 (varies by lot)
Sequence Positions
314-343
Sequence Length
395
Applicable Applications for anti-GTF2H2C antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot (WB)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Crown Antibody
Yes
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(GTF2H2C Antibody(C-term) western blot analysis in A549,K562,MCF-7 cell line lysates (35ug/lane).This demonstrates the GTF2H2C antibody detected the GTF2H2C protein (arrow).)

Western Blot (WB) (GTF2H2C Antibody(C-term) western blot analysis in A549,K562,MCF-7 cell line lysates (35ug/lane).This demonstrates the GTF2H2C antibody detected the GTF2H2C protein (arrow).)

Immunohistochemistry (IHC)

(GTF2H2C Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GTF2H2C Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (GTF2H2C Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GTF2H2C Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunofluorescence (IF)

(Confocal immunofluorescent analysis of GTF2H2C Antibody (C-term) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).)

Immunofluorescence (IF) (Confocal immunofluorescent analysis of GTF2H2C Antibody (C-term) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).)
Related Product Information for anti-GTF2H2C antibody
Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II (By similarity).
Product Categories/Family for anti-GTF2H2C antibody
References
Schmutz, J., et al. Nature 431(7006):268-274(2004)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
44452
NCBI Official Full Name
general transcription factor IIH subunit 2-like protein
NCBI Official Synonym Full Names
GTF2H2 family member C, copy 2
NCBI Official Symbol
GTF2H2C_2
NCBI Official Synonym Symbols
GTF2H2D
NCBI Protein Information
general transcription factor IIH subunit 2-like protein
UniProt Protein Name
General transcription factor IIH subunit 2-like protein
UniProt Gene Name
GTF2H2C
UniProt Synonym Gene Names
GTF2H2D
UniProt Entry Name
T2H2L_HUMAN

Uniprot Description

GTF2H2C: Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. Belongs to the GTF2H2 family.

Chromosomal Location of Human Ortholog: 5q13.2

Molecular Function: zinc ion binding

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; nucleotide-excision repair

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Product Notes

The GTF2H2C gtf2h2c (Catalog #AAA9209005) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 314-343. The GTF2H2C Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GTF2H2C can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot (WB). WB~~1:1000. Researchers should empirically determine the suitability of the GTF2H2C gtf2h2c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GTF2H2C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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