Rabbit anti-Human GPR55 Polyclonal Antibody | anti-GPR55 antibody

GPR55 Rabbit pAb

Cat. Num. AAA4755015

• Gene Names: GPR55; LPIR1
• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity purified
• Synonyms: GPR55; Polyclonal Antibody; GPR55 Rabbit pAb; anti-GPR55 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Purity/Purification: Affinity purified
• Form/Format: -20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

• Applicable Applications for anti-GPR55 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
• Application Notes: WB: 1:500-1:2000
• Immunogen: Synthetic peptide of human GPR55
• Conjugation: Unconjugated
• Molecular Function: This gene belongs to the G-protein-coupled receptor superfamily. The encoded integral membrane protein is a likely cannabinoid receptor. It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways.
• Modification: Unmodified
• Preparation and Storage: Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: PC-3 cell lysate, Primary antibody: 163583(GPR55 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes)

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 163583(GPR55 Antibody) at dilution 1/40. (Original magnification: ×200))

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 163583(GPR55 Antibody) at dilution 1/40. (Original magnification: ×200))

Product Categories/Family for anti-GPR55 antibody

Primary antibody

NCBI and Uniprot Product Information

• NCBI GI #: 33695107
• NCBI GeneID: 9290
• NCBI Accession #: NP_005674
• NCBI GenBank Nucleotide #: NM_005683.3
• UniProt Accession #: Q9Y2T6; Q8N580
• Molecular Weight: 37 kDa
• NCBI Official Full Name: G-protein coupled receptor 55
• NCBI Official Synonym Full Names: G protein-coupled receptor 55
• NCBI Official Symbol: GPR55
• NCBI Official Synonym Symbols: LPIR1
• NCBI Protein Information: G-protein coupled receptor 55
• UniProt Protein Name: G-protein coupled receptor 55
• Protein Family: G-protein coupled receptor
• UniProt Gene Name: GPR55
• UniProt Entry Name: GPR55_HUMAN

NCBI Description

This gene belongs to the G-protein-coupled receptor superfamily. The encoded integral membrane protein is a likely cannabinoid receptor. It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways. [provided by RefSeq, Aug 2013]

Uniprot Description

GPR55: May be involved in hyperalgesia associated with inflammatory and neuropathic pain. Receptor for L- alpha-lysophosphatidylinositol (LPI). LPI induces Ca(2+) release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. Putative cannabinoid receptor. May play a role in bone physiology by regulating osteoclast number and function. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 2q37

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; cannabinoid receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of osteoclast differentiation; phospholipase C activation; positive regulation of Rho protein signal transduction; bone resorption