Rabbit GPBP1 Polyclonal Antibody | anti-GPBP1 antibody

GPBP1 Rabbit Polyclonal

Cat. Num. AAA769809

• Gene Names: GPBP1; GPBP; SSH6; VASCULIN
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: GPBP1; Polyclonal Antibody; GPBP1 Rabbit Polyclonal; anti-GPBP1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 392

• Applicable Applications for anti-GPBP1 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: GC-rich promoter binding protein 1
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human small intestine slide using MBS769809 (GPBP1 Antibody) at dilution of 1:50)

Western Blot (WB)

(HepG2 cells were subjected to SDS PAGE followed by western blot with MBS769809 (GPBP1 antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

• NCBI GI #: 47124485
• NCBI GeneID: 65056
• Molecular Weight: 33,830 Da
• NCBI Official Full Name: GPBP1 protein, partial
• NCBI Official Synonym Full Names: GC-rich promoter binding protein 1
• NCBI Official Symbol: GPBP1
• NCBI Official Synonym Symbols: GPBP; SSH6; VASCULIN
• NCBI Protein Information: vasculin
• UniProt Protein Name: Vasculin
• Protein Family: Vasculin
• UniProt Gene Name: GPBP1
• UniProt Synonym Gene Names: GPBP; SSH6
• UniProt Entry Name: GPBP1_HUMAN

NCBI Description

This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]

Uniprot Description

GPBP1: a novel vascular protein differentially expressed in human atherogenesis. Can be found in the plasma, thus it may be a possible marker for atherosclerosis.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 5q11.2

Cellular Component: cytoplasm; intracellular membrane-bound organelle; nucleoplasm; nucleus

Molecular Function: DNA binding; protein binding; transcription factor activity

Biological Process: positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent; transcription, DNA-dependent