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Western Blot (WB) (Western blot analysis of Human plasma solution using HBG1:HBG2 Polyclonal Antibody at dilution of 1:350)

Rabbit anti-Human HBG1/HBG2 Polyclonal Antibody | anti-HBG1/HBG2 antibody

HBG1/HBG2 Polyclonal Antibody

Gene Names
HBG1; HBGA; HBGR; HBG-T2; HSGGL1; PRO2979
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Antigen Affinity Purification
Synonyms
HBG1/HBG2; Polyclonal Antibody; HBG1/HBG2 Polyclonal Antibody; A gamma globin; G gamma globin; Gamma 1 globin; Gamma 2 globin; Gamma A hemoglobin; Gamma globin; Hb F Agamma; Hb F Ggamma; Hbfagamma; Hbfggamma; HBG 1; HBG 2; HBG1; HBG2; HBGA; HBGR; Hemoglobin gamma 1 chain; Hemoglobin gamma 2 chain; Hemoglobin gamma A; Hemoglobin gamma A chain; Hemoglobin gamma G; Hemoglobin gamma G chain; Hemoglobin gamma regulator of; Hemoglobin subunit gamma 1; Hemoglobin subunit gamma 2; HSGGL 1; HSGGL1; Methemoglobin; PRO 2979; PRO2979; anti-HBG1/HBG2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
0.84mg/mL (varies by lot)
Sequence Length
147
Applicable Applications for anti-HBG1/HBG2 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
IHC: 1:50-1:300
ELISA: 1:5000-1:10000
Immunogen
Fusion protein of human HBG1/HBG2
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of Human plasma solution using HBG1:HBG2 Polyclonal Antibody at dilution of 1:350)

Western Blot (WB) (Western blot analysis of Human plasma solution using HBG1:HBG2 Polyclonal Antibody at dilution of 1:350)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using HBG1:HBG2 Polyclonal Antibody at dilution of 1:100(×200))

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using HBG1:HBG2 Polyclonal Antibody at dilution of 1:100(×200))

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using HBG1:HBG2 Polyclonal Antibody at dilution of 1:100(×200))

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using HBG1:HBG2 Polyclonal Antibody at dilution of 1:100(×200))
Related Product Information for anti-HBG1/HBG2 antibody
The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Product Categories/Family for anti-HBG1/HBG2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16 kDa
NCBI Official Full Name
hemoglobin subunit gamma-1
NCBI Official Synonym Full Names
hemoglobin subunit gamma 1
NCBI Official Symbol
HBG1
NCBI Official Synonym Symbols
HBGA; HBGR; HBG-T2; HSGGL1; PRO2979
NCBI Protein Information
hemoglobin subunit gamma-1
UniProt Protein Name
Hemoglobin subunit gamma-1
UniProt Gene Name
HBG1
UniProt Entry Name
HBG1_HUMAN

NCBI Description

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008]

Uniprot Description

HBG1: Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. Belongs to the globin family.

Protein type: Carrier

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: hemoglobin complex; cytosol

Molecular Function: iron ion binding; heme binding; oxygen binding; oxygen transporter activity

Biological Process: oxygen transport; blood coagulation

Disease: Fetal Hemoglobin Quantitative Trait Locus 1

Research Articles on HBG1/HBG2

Similar Products

Product Notes

The HBG1/HBG2 hbg1 (Catalog #AAA2562592) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HBG1/HBG2 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HBG1/HBG2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500-1:2000 IHC: 1:50-1:300 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the HBG1/HBG2 hbg1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HBG1/HBG2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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