Western Blot (WB)
(Western Blot analysis of GNA15 expression in transfected 293T cell line by GNA15 polyclonal antibody. Lane 1: GNA15 transfected lysate (41.25kD). Lane 2: Non-transfected lysate.)
Mouse anti-Human GNA15 Polyclonal Antibody | anti-GNA15 antibody
GNA15 (Guanine Nucleotide-binding Protein Subunit alpha-15, G alpha-15, G-protein Subunit alpha-15, Epididymis Tissue Protein Li 17E, Guanine Nucleotide-binding Protein Subunit alpha-16, G alpha-16, G-protein Subunit alpha-16, GNA16)
Gene Names
GNA15; GNA16
Reactivity
Human
Applications
Western Blot
Purity
Affinity PurifiedPurified by Protein A affinity chromatography.
Synonyms
GNA15; Polyclonal Antibody; GNA15 (Guanine Nucleotide-binding Protein Subunit alpha-15; G alpha-15; G-protein Subunit alpha-15; Epididymis Tissue Protein Li 17E; Guanine Nucleotide-binding Protein Subunit alpha-16; G alpha-16; G-protein Subunit alpha-16; GNA16); Anti -GNA15 (Guanine Nucleotide-binding Protein Subunit alpha-15; anti-GNA15 antibody
Host
Mouse
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human GNA15.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Sequence
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
Applicable Applications for anti-GNA15 antibody
Western Blot (WB)
Application Notes
Suitable for use in Western Blot.
Immunogen
Full length human GNA15, aa1-374 (AAH13585.1).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(Western Blot analysis of GNA15 expression in transfected 293T cell line by GNA15 polyclonal antibody. Lane 1: GNA15 transfected lysate (41.25kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of GNA15 expression in transfected 293T cell line by GNA15 polyclonal antibody. Lane 1: GNA15 transfected lysate (41.25kD). Lane 2: Non-transfected lysate.)
Related Product Information for anti-GNA15 antibody
Ga16 is the only heterotrimeric G protein with a restricted expression pattern in hematopoietic cells. Differentiation of promyelocytic cells leads to decreased expression of Ga16. The G protein is known to couple a large number of G protein-coupled receptors to PLC-b and can lead to production of the secondary messengers diacylglycerol and inositol phosphates. Targeted deletion of Ga15, a mouse orthologue of human Ga16, causes reduced C5a receptor signaling. Ga16 serves as a marker, in addition to CD34, for hematopoietic progenitor cells.
Product Categories/Family for anti-GNA15 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
43,568 Da
NCBI Official Full Name
guanine nucleotide-binding protein subunit alpha-15
NCBI Official Synonym Full Names
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
NCBI Official Symbol
GNA15
NCBI Official Synonym Symbols
GNA16
NCBI Protein Information
guanine nucleotide-binding protein subunit alpha-15; g alpha-15; g alpha-16; G-protein subunit alpha-15; G-protein subunit alpha-16; epididymis tissue protein Li 17E; guanine nucleotide-binding protein subunit alpha-16
UniProt Protein Name
Guanine nucleotide-binding protein subunit alpha-15
Protein Family
UniProt Gene Name
GNA15
UniProt Synonym Gene Names
GNA16; G alpha-15; G-protein subunit alpha-15; G alpha-16
UniProt Entry Name
GNA15_HUMAN
Uniprot Description
G-alpha 15: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Belongs to the G-alpha family. G(q) subfamily.
Protein type: G protein; G protein, heterotrimeric alpha G(q); G protein, heterotrimeric
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: plasma membrane; heterotrimeric G-protein complex
Molecular Function: GTPase activity; signal transducer activity; GTP binding; G-protein-coupled receptor binding; metal ion binding; G-protein beta/gamma-subunit binding
Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; platelet activation; elevation of cytosolic calcium ion concentration; phospholipase C activation; metabolic process; dopamine receptor, phospholipase C activating pathway; blood coagulation; muscarinic acetylcholine receptor, phospholipase C activating pathway
Research Articles on GNA15
Similar Products
Product Notes
The GNA15 gna15 (Catalog #AAA641334) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The GNA15 (Guanine Nucleotide-binding Protein Subunit alpha-15, G alpha-15, G-protein Subunit alpha-15, Epididymis Tissue Protein Li 17E, Guanine Nucleotide-binding Protein Subunit alpha-16, G alpha-16, G-protein Subunit alpha-16, GNA16) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GNA15 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the GNA15 gna15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MARSLTWRCC PWCLTEDEKA AARVDQEINR ILLEQKKQDR GELKLLLLGP GESGKSTFIK QMRIIHGAGY SEEERKGFRP LVYQNIFVSM RAMIEAMERL QIPFSRPESK HHASLVMSQD PYKVTTFEKR YAAAMQWLWR DAGIRACYER RREFHLLDSA VYYLSHLERI TEEGYVPTAQ DVLRSRMPTT GINEYCFSVQ KTNLRIVDVG GQKSERKKWI HCFENVIALI YLASLSEYDQ CLEENNQENR MKESLALFGT ILELPWFKST SVILFLNKTD ILEEKIPTSH LATYFPSFQG PKQDAEAAKR FILDMYTRMY TGCVDGPEGS KKGARSRRLF SHYTCATDTQ NIRKVFKDVR DSVLARYLDE INLL. It is sometimes possible for the material contained within the vial of "GNA15, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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