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Testing Data

Rabbit anti-Mouse GM-CSF Polyclonal Antibody | anti-GM-CSF antibody

GM-CSF Antibody

Gene Names
Csf2; Csfgm; GMCSF; Gm-CSf; MGI-IGM
Reactivity
Mouse
Applications
Western Blot, Neutralization Assay
Purity
Affinity purified
Synonyms
GM-CSF; Polyclonal Antibody; GM-CSF Antibody; Granulocyte-macrophage colony-stimulating factor; GMCSF; Colony-stimulating factor; CSF; Sargramostim; Molgramostin; anti-GM-CSF antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
100ug (0.5 mg/ml) affinity purified rabbit anti-murine GM-CSF polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% thimerosal.
Appearance: Colorless liquid
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
141
Applicable Applications for anti-GM-CSF antibody
Western Blot (WB), Neutralization
Application Notes
Western blot analysis (0.5-4 ug/ml). Recombinant murine GM-CSF can be used as a positive control. Based on researchers feedback, the antibody also works well in ELISA (2-3 ug/ml) and neutralization (5-10 ug/ml). However, the optimal conditions should be determined individually.
Immunogen
E. coli expressed murine GM-CSF
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months

Testing Data

Testing Data
Related Product Information for anti-GM-CSF antibody
Background: Murine GM-CSF (Granulocyte Macrophage Colony Stimulating Factor) is a potent species-specific stimulator of bone marrow cells. GM-CSF stimulates precursor cells of granulocytes, macrophages and eosinophils. Murine GM-CSF is a 14.0 kDa protein containing 124 amino acid residues.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
16,091 Da
NCBI Official Full Name
unnamed protein product
NCBI Official Synonym Full Names
colony stimulating factor 2 (granulocyte-macrophage)
NCBI Official Symbol
Csf2
NCBI Official Synonym Symbols
Csfgm; GMCSF; Gm-CSf; MGI-IGM
NCBI Protein Information
granulocyte-macrophage colony-stimulating factor
UniProt Protein Name
Granulocyte-macrophage colony-stimulating factor
UniProt Gene Name
Csf2
UniProt Synonym Gene Names
Csfgm; GM-CSF; CSF
UniProt Entry Name
CSF2_MOUSE

Uniprot Description

GMCSF: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Belongs to the GM-CSF family.

Protein type: Cytokine; Secreted; Secreted, signal peptide

Cellular Component: extracellular space; extracellular region

Molecular Function: growth factor activity; granulocyte macrophage colony-stimulating factor receptor binding; cytokine activity

Biological Process: negative regulation of cytolysis; epithelial fluid transport; macrophage activation; embryonic placenta development; positive regulation of tyrosine phosphorylation of Stat5 protein; positive regulation of interleukin-23 production; regulation of gene expression; positive regulation of cell proliferation; immune response; myeloid dendritic cell differentiation; positive regulation of DNA replication; regulation of cell proliferation

Research Articles on GM-CSF

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Product Notes

The GM-CSF csf2 (Catalog #AAA840188) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GM-CSF Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GM-CSF can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Neutralization. Western blot analysis (0.5-4 ug/ml). Recombinant murine GM-CSF can be used as a positive control. Based on researchers feedback, the antibody also works well in ELISA (2-3 ug/ml) and neutralization (5-10 ug/ml). However, the optimal conditions should be determined individually. Researchers should empirically determine the suitability of the GM-CSF csf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GM-CSF, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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