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Rabbit anti-Human GLDN Polyclonal Antibody | anti-GLDN antibody

GLDN (Center) Rabbit pAb

Reactivity
Human
Applications
Western Blot
Purity
Affinity Purified
Synonyms
GLDN; Polyclonal Antibody; GLDN (Center) Rabbit pAb; Gliomedin; COLM; anti-GLDN antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Ig
Clone Number
RB36176
Purity/Purification
Affinity Purified
Form/Format
Supplied in PBS with 0.09% (W/V) Sodium Azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Length
551
Applicable Applications for anti-GLDN antibody
Western Blot (WB)
Application Notes
WB: 1:1000
Immunogen
This GLDN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-299 amino acids from the central region of human GLDN.
Cellular Localization
Cell Membrane, Cell Projection, Extracellular Matrix, Membrane, Secreted

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
gliomedin isoform 1
UniProt Protein Name
Gliomedin
Protein Family
UniProt Gene Name
GLDN
UniProt Synonym Gene Names
COLM

Uniprot Description

Ligand for NRCAM and NFASC/neurofascin that plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Mediates interaction between Schwann cell microvilli and axons via its interactions with NRCAM and NFASC. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters. Required, together with NRCAM, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier.

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Product Notes

The GLDN gldn (Catalog #AAA8552958) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GLDN (Center) Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GLDN can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000. Researchers should empirically determine the suitability of the GLDN gldn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GLDN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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