Immunohistochemistry (IHC)
(Anti-GHBP/BLVRB antibody IHC staining of human spleen, erythrocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Goat anti-Human GHBP/BLVRB Polyclonal Antibody | anti-GHBP/BLVRB antibody
Anti-GHBP/BLVRB Antibody (aa38-49)
Gene Names
BLVRB; FLR; BVRB; SDR43U1; HEL-S-10
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
GHBP/BLVRB; Polyclonal Antibody; Anti-GHBP/BLVRB Antibody (aa38-49); Rabbit Polyclonal (IgG) to Human GHBP/BLVRB; BLVRB; Biliverdin-IX beta-reductase; BVR-B; Flavin reductase (NADPH); Green heme-binding protein; Flavin reductase; FR; SDR43U1; NADPH-dependent diaphorase; NADPH-flavin reductase; Biliverdin reductase B; BVRB; FLR; GHBP; anti-GHBP/BLVRB antibody
Host
Goat
Reactivity
Human
Clonality
Polyclonal
Specificity
Human GHBP/BLVRB
Purity/Purification
Immunoaffinity Purified
Form/Format
Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Sequence Length
206
Applicable Applications for anti-GHBP/BLVRB antibody
ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
ELISA: 1:128000
IHC-P: 5 ug/ml
WB: 0.1-0.3 ug/ml
IHC-P: 5 ug/ml
WB: 0.1-0.3 ug/ml
Immunogen
Synthetic peptide C-SRLPSEGPRPAH from an internal region of human GHBP/BLVRB (NP_000704.1). Percent identity by BLAST analysis: Human (100%); Chimpanzee, Gorilla, Gibbon, Monkey, Mouse, Rat, Bovine, Bat (92%); Ferret, Elephant, Panda, Rabbit, Horse, Pig, Guinea pig (83%).
Conjugation
Unconjugated
Epitope
aa38-49
Preparation and Storage
Store at -20 degree C.
Avoid freeze-thaw cycles.
Avoid freeze-thaw cycles.
Immunohistochemistry (IHC)
(Anti-GHBP/BLVRB antibody IHC staining of human spleen, erythrocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (IHC)
(Anti-GHBP/BLVRB antibody IHC staining of human spleen, erythrocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Immunohistochemistry (WB)
(Anti-GHBP/BLVRB antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunohistochemistry (WB)
(Anti-GHBP/BLVRB antibody IHC staining of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Western Blot (WB)
(GHBP Antibody (0.1ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
(GHBP Antibody (0.1ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Related Product Information for anti-GHBP/BLVRB antibody
Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe3+ iron to Fe2+ in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
22,119 Da
NCBI Official Full Name
flavin reductase (NADPH)
NCBI Official Synonym Full Names
biliverdin reductase B
NCBI Official Symbol
BLVRB
NCBI Official Synonym Symbols
FLR; BVRB; SDR43U1; HEL-S-10
NCBI Protein Information
flavin reductase (NADPH)
UniProt Protein Name
Flavin reductase (NADPH)
UniProt Gene Name
BLVRB
UniProt Synonym Gene Names
FLR; BVR-B; GHBP; FLR
NCBI Description
The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B (EC 1.3.1.24).[supplied by OMIM, Jul 2009]
Uniprot Description
Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe3+ iron to Fe2+ in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.
Research Articles on GHBP/BLVRB
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Product Notes
The GHBP/BLVRB blvrb (Catalog #AAA2401057) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Anti-GHBP/BLVRB Antibody (aa38-49) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GHBP/BLVRB can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). ELISA: 1:128000 IHC-P: 5 ug/ml WB: 0.1-0.3 ug/ml. Researchers should empirically determine the suitability of the GHBP/BLVRB blvrb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GHBP/BLVRB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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