Western Blot (WB)
(Western blot analysis of lysates from human liver and mouse liver tissue lysate(from left to right), using BLVRB Antibody (C-term). MBS9214641 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
Rabbit BLVRB Polyclonal Antibody | anti-BLVRB antibody
BLVRB Antibody (C-term)
Western Blot (WB)
(Western blot analysis of lysates from human liver and mouse liver tissue lysate(from left to right), using BLVRB Antibody (C-term). MBS9214641 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
Western Blot (WB)
(Western blot analysis of lysates from human liver and mouse liver tissue lysate(from left to right), using BLVRB Antibody (C-term). MBS9214641 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.)
Cellular Location: Cytoplasm.
Tissue Location: Predominantly expressed in liver and erythrocytes. At lower levels in heart, lung, adrenal gland and cerebrum.
Komuro A.,et al.Biol. Pharm. Bull. 19:796-804(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
NCBI and Uniprot Product Information
NCBI Description
The final step in heme metabolism in mammals is catalyzed by the cytosolic biliverdin reductase enzymes A and B (EC 1.3.1.24).[supplied by OMIM, Jul 2009]
Uniprot Description
BLVRB: Broad specificity oxidoreductase that catalyzes the NADPH-dependent reduction of a variety of flavins, such as riboflavin, FAD or FMN, biliverdins, methemoglobin and PQQ (pyrroloquinoline quinone). Contributes to heme catabolism and metabolizes linear tetrapyrroles. Can also reduce the complexed Fe(3+) iron to Fe(2+) in the presence of FMN and NADPH. In the liver, converts biliverdin to bilirubin.
Protein type: Cofactor and Vitamin Metabolism - porphyrin and chlorophyll; EC 1.3.1.24; Oxidoreductase; EC 1.5.1.30
Chromosomal Location of Human Ortholog: 19q13.1-q13.2
Cellular Component: nucleoplasm; cytoplasm; plasma membrane; cytosol
Molecular Function: flavin reductase activity; biliverdin reductase activity
Biological Process: heme catabolic process; porphyrin metabolic process
Research Articles on BLVRB
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Product Notes
The BLVRB blvrb (Catalog #AAA9214641) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BLVRB Antibody (C-term) reacts with Human, mouse (Predicted Reactivity: Bovine) and may cross-react with other species as described in the data sheet. AAA Biotech's BLVRB can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB~~1:1000. Researchers should empirically determine the suitability of the BLVRB blvrb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BLVRB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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