Western Blot (WB)
(GCHFR Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the GCHFR antibody detected the GCHFR protein (arrow).)
Rabbit GCHFR Polyclonal Antibody | anti-GCHFR antibody
GCHFR Antibody (C-term)
Western Blot (WB)
(GCHFR Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the GCHFR antibody detected the GCHFR protein (arrow).)
Western Blot (WB)
(GCHFR Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the GCHFR antibody detected the GCHFR protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
GTP cyclohydrolase I feedback regulatory protein binds to and mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase I. The regulatory protein, GCHFR, consists of a homodimer. It is postulated that GCHFR may play a role in regulating phenylalanine metabolism in the liver and in the production of biogenic amine neurotransmitters and nitric oxide. [provided by RefSeq, Jul 2008]
Uniprot Description
GCHFR: Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine. Belongs to the GFRP family.
Protein type: Inhibitor
Chromosomal Location of Human Ortholog: 15q15
Cellular Component: nuclear membrane; protein complex; dendrite; cytoplasm; melanosome; cytosol; nucleus
Molecular Function: enzyme inhibitor activity; amino acid binding; protein binding; GTP-dependent protein binding
Biological Process: negative regulation of biosynthetic process; neurotransmitter metabolic process; protein heterooligomerization; negative regulation of GTP cyclohydrolase I activity; regulation of nitric-oxide synthase activity; nitric oxide biosynthetic process; nitric oxide metabolic process
Research Articles on GCHFR
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Product Notes
The GCHFR gchfr (Catalog #AAA9214237) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 38-66. The GCHFR Antibody (C-term) reacts with Human (Predicted Reactivity: Bovine) and may cross-react with other species as described in the data sheet. AAA Biotech's GCHFR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the GCHFR gchfr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GCHFR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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