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Immunohistochemistry (IHC) (Anti-GALR3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit GALR3 / Galanin Receptor 3 Polyclonal Antibody | anti-GALR3 antibody

Rabbit Polyclonal to Human GALR3 / Galanin Receptor 3

Reactivity
Bovine, Gorilla, Human, Monkey, Mouse, Pig, Rat
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
GALR3 / Galanin Receptor 3; Polyclonal Antibody; Rabbit Polyclonal to Human GALR3 / Galanin Receptor 3; Anti-GALR3 / Galanin Receptor 3 Antibody (Extracellular Domain) IHC-plus; GALR3; Gal receptor-3; Galanin r3 receptor; Gal-r3; Galanin receptor 3; Galanin receptor galr3; Galanin receptor subtype 3; Gal3 receptor; GAL3-R; Galanin 2 receptor homolog; Galanin receptor type 3; GALNR3; GALR-3; Human GALR3; Galanin Receptor 3; anti-GALR3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Bovine, Gorilla, Human, Monkey, Mouse, Pig, Rat
Clonality
Polyclonal
Specificity
Human GALR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
368
Applicable Applications for anti-GALR3 antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (28 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from 3rd extracellular domain of human GALR3. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Rat, Bovine, Pig (100%); Elephant (94%); Dog, Rabbit (88%).
Immunogen Type
Synthetic peptide
Immunogen
GALR3 / Galanin Receptor 3 antibody was raised against synthetic 17 amino acid peptide from 3rd extracellular domain of human GALR3. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Rat, Bovine, Pig (100%); Elephant (94%); Dog, Rabbit (88%).
Antigen Modification
Extracellular Domain
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-GALR3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-GALR3 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-GALR3 antibody
GalR3 is a Galanin Receptor that is similar, but distinct from the other galanin receptors, and it mediates the effects of the galanin peptide in a wide variety of tissues. Like GalR1, the signaling mechanism is predominantly through inhibition of adenylate cyclase.
Product Categories/Family for anti-GALR3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
39,573 Da
NCBI Official Full Name
galanin receptor type 3
NCBI Official Synonym Full Names
galanin receptor 3
NCBI Official Symbol
GALR3
NCBI Protein Information
galanin receptor type 3; GAL3-R; GALR-3; galanin receptor, family member 3
UniProt Protein Name
Galanin receptor type 3
Protein Family
UniProt Gene Name
GALR3
UniProt Synonym Gene Names
GALNR3; GAL3-R; GALR-3
UniProt Entry Name
GALR3_HUMAN

NCBI Description

The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcripts [provided by RefSeq, Jul 2008]

Uniprot Description

GALR3: Receptor for the hormone galanin. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: plasma membrane; integral to membrane

Molecular Function: peptide hormone binding; galanin receptor activity

Biological Process: synaptic transmission; learning and/or memory; neuropeptide signaling pathway; negative regulation of adenylate cyclase activity; feeding behavior; positive regulation of transcription from RNA polymerase II promoter; G-protein signaling, adenylate cyclase inhibiting pathway

Research Articles on GALR3

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Product Notes

The GALR3 galr3 (Catalog #AAA244303) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human GALR3 / Galanin Receptor 3 reacts with Bovine, Gorilla, Human, Monkey, Mouse, Pig, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GALR3 / Galanin Receptor 3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (28 ug/ml). Researchers should empirically determine the suitability of the GALR3 galr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GALR3 / Galanin Receptor 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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