Goat anti-Human GALR3 Polyclonal Antibody | anti-GALR3 antibody

GALR3, CT (Galanin Receptor Type 3, GAL3-R, GALR-3, GALNR3)

Cat. Num. AAA644066

• Reactivity: Human
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: GALR3; Polyclonal Antibody; CT (Galanin Receptor Type 3; GAL3-R; GALR-3; GALNR3); Anti -GALR3; anti-GALR3 antibody

• Host: Goat
• Reactivity: Human
• Clonality: Polyclonal
• Specificity: Recognizes human GALR3.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.

• Applicable Applications for anti-GALR3 antibody: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: Suitable for use in ELISA, Western Blot and Immunohistochemistry.; Dilution: ELISA: 1:32,000; Western Blot: 1-3ug/ml; Immunohistochemistry (Formalin fixed paraffin embedded): 3.75ug/ml
• Immunogen: Synthetic peptide C-QGPEPREGPVHGGE from the C-terminus of human GALR3.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunohistochemistry (IHC)

(Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE))

Chemiluminescence

(Antibody (2ug/ml) staining of human skin lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Related Product Information for anti-GALR3 antibody

GalR3 is a Galanin Receptor that is similar, but distinct from the other galanin receptors, and it mediates the effects of the galanin peptide in a wide variety of tissues. Like GalR1, the signaling mechanism is predominantly through inhibition of adenylate cyclase.

Product Categories/Family for anti-GALR3 antibody

Antibodies; Abs to Receptors

NCBI and Uniprot Product Information

• NCBI GI #: 4503907
• NCBI GeneID: 8484
• NCBI Accession #: NP_003605.1
• NCBI GenBank Nucleotide #: NM_003614.1
• UniProt Accession #: O60755; Q53YJ4
• Molecular Weight: 39,573 Da
• NCBI Official Full Name: galanin receptor type 3
• NCBI Official Synonym Full Names: galanin receptor 3
• NCBI Official Symbol: GALR3
• NCBI Protein Information: galanin receptor type 3; GAL3-R; GALR-3; galanin receptor, family member 3
• UniProt Protein Name: Galanin receptor type 3
• Protein Family: Galanin receptor
• UniProt Gene Name: GALR3
• UniProt Synonym Gene Names: GALNR3; GAL3-R; GALR-3
• UniProt Entry Name: GALR3_HUMAN

NCBI Description

The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcripts [provided by RefSeq, Jul 2008]

Uniprot Description

GALR3: Receptor for the hormone galanin. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1

Chromosomal Location of Human Ortholog: 22q13.1

Cellular Component: plasma membrane; integral to membrane

Molecular Function: peptide hormone binding; galanin receptor activity

Biological Process: synaptic transmission; learning and/or memory; neuropeptide signaling pathway; negative regulation of adenylate cyclase activity; feeding behavior; positive regulation of transcription from RNA polymerase II promoter; G-protein signaling, adenylate cyclase inhibiting pathway